PFN1 antibody (Center)

Catalog No. ABIN2855281

Product Details anti-PFN1 Antibody

Target: PFN1 (Profilin 1 (PFN1))

Binding Specificity: Center

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PFN1 antibody is un-conjugated

Application: Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)

Cross-Reactivity: Rat (Rattus), Cow (Bovine)

Cross-Reactivity (Details): Rat (95 %), Bovine (93 %)

Characteristics: Rabbit Polyclonal antibody to Profilin 1 (profilin 1)
Profilin 1 antibody [N1C3]

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human Profilin 1. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: Suggested dilution Reference ICC/IF Assay-dependent dilution IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceICC/IFAssay-dependent dilution IHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Western blot1:500-1:3000*

Comment:

Positive Control: 293T , A431 , HeLa , HepG2 , mouse spleen

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.56 mg/mL

Buffer: 1XPBS, 1 % BSA, 20 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for PFN1

Target: PFN1 (Profilin 1 (PFN1))

Alternative Name: Profilin 1 (PFN1 Products)

Synonyms: GmPRO1 antibody, GmPRO2 antibody, PRO1 antibody, Profilin-1 antibody, profilin-1 antibody, profilin antibody, MGC130883 antibody, Profilin1 antibody, XProfilin1 antibody, sb:cb813 antibody, wu:fa91a03 antibody, ALS18 antibody, Pfn antibody, F6F22.21 antibody, F6F22_21 antibody, PFN1 antibody, PROFILIN 1 antibody, profilin 1 antibody, profilin antibody, profilin 1 antibody, profilin 1 L homeolog antibody, profilin homolog 1 antibody, Profilin-1 antibody, PRO2 antibody, PFN1 antibody, pfn1.L antibody, pfn1 antibody, Pfn1 antibody, PRF1 antibody, prf1 antibody, pfn-1 antibody

Background: The protein encoded by this gene is a ubiquitous actin monomer-binding protein belonging to the profilin family. It is thought to regulate actin polymerization in response to extracellular signals. Deletion of this gene is associated with Miller-Dieker syndrome.

Cellular Localization: Cytoplasm , cytoskeleton

Molecular Weight: 15 kDa

Gene ID: 5216

Pathways: Regulation of Actin Filament Polymerization, Tube Formation, Maintenance of Protein Location