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SNCAIP antibody

SNCAIP Reactivity: Human WB, ELISA, IHC Host: Goat Polyclonal unconjugated
Catalog No. ABIN285957
  • Target See all SNCAIP Antibodies
    SNCAIP (Synuclein, alpha Interacting Protein (SNCAIP))
    Reactivity
    • 20
    • 17
    • 16
    • 1
    Human
    Host
    • 31
    • 2
    • 1
    Goat
    Clonality
    • 33
    • 1
    Polyclonal
    Conjugate
    • 16
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SNCAIP antibody is un-conjugated
    Application
    • 28
    • 13
    • 13
    • 12
    • 6
    • 4
    • 3
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    Immunogen
    Synphilin 1 antibody was raised in goat using a peptide, SLELNGEKDKDKGRTLQRT, as the immunogen.
    Top Product
    Discover our top product SNCAIP Primary Antibody
  • Application Notes
    ELISA: >1:10,655, IHC-P: >1:400, WB: >1:2,000
    Optimal conditions should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Supplied as liquid whole serum without preservative
    Handling Advice
    Avoid repeated freeze/thaw cycles.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store at 4 °C for short term storage. Aliquot and store at -20 °C for long term storage.
  • Target
    SNCAIP (Synuclein, alpha Interacting Protein (SNCAIP))
    Alternative Name
    Synphilin 1 (SNCAIP Products)
    Background
    Synphilin-1 is a cytoplasmic protein that is enriched in the neurophil of normal human brain. Although the exact function of synphilin-1 is unknown, it may possibly have a role as a cytoskeletal protein based on the presence of ankyrin-like repeats and an ATP, GTP-binding domain. It has been shown to be novel is its ability to associate in vivo with a-synuclein to form cytoplasmic eosinophilic inclusions. Additionally, it has been observed to be present in Lewy bodies of Parkinson disease, which are composed of a-synuclein. Because synphilin-1 is not found in protein aggregates of Alzheimer’s disease, it appears to be specific for a-synuclein-containing lesions. Synphilin-1 may facilitate the aggregation of a-synuclein into Lewy bodies.
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