Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

GFAP antibody (Glial Fibrillary Acidic Protein) Primary Antibody

GFAP Reactivity: Human, Mouse, Rat, Zebrafish (Danio rerio) IHC (fro), IHC (p), IHC, WB Host: Rabbit Polyclonal K39 unconjugated
Pubmed (2)
Catalog No. ABIN335275
$314.77
Plus shipping costs $45.00
0.1 mL
local_shipping Shipping to: United States
Delivery in 5 to 7 Business Days
  • Target
    GFAP
    Reactivity
    • 339
    • 184
    • 171
    • 76
    • 71
    • 48
    • 46
    • 11
    • 11
    • 11
    • 9
    • 8
    • 8
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat, Zebrafish (Danio rerio)
    Host
    • 215
    • 147
    • 13
    • 11
    • 3
    • 2
    • 1
    Rabbit
    Clonality
    • 227
    • 164
    Polyclonal
    Conjugate
    • 192
    • 32
    • 22
    • 21
    • 13
    • 10
    • 9
    • 7
    • 7
    • 5
    • 5
    • 5
    • 5
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This GFAP antibody is un-conjugated
    Application
    • 280
    • 140
    • 122
    • 101
    • 90
    • 64
    • 59
    • 36
    • 29
    • 26
    • 26
    • 24
    • 15
    • 10
    • 8
    • 6
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (IHC), Western Blotting (WB)
    Specificity
    Human, mouse and rat.
    Purification
    Antiserum
    Immunogen
    K39 is a rabbit polyclonal antiserum derived by immunization of a rabbit with a glial fibrillary acidic protein preparation from human spinal cord.
    Clone
    K39
  • Application Notes
    K39 reacts exclusively with glial fibrillary acidic protein which is present in astrocytes in the central nervous system and Schwann cells. K39 is suitable for immunoblotting and immunohistochemistry on frozen and paraffin-embedded tissues. Optimal antibody dilution should be determined by titration, recommended range is 1:100 - 1:200 for immunohistochemistry with avidin-biotinylated horseradish peroxidase complex (ABC) as detection reagent, and 1:100 - 1:1000 for immunoblotting applications.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Storage
    4 °C
  • Herpers, Ramaekers, Aldeweireldt, Moesker, Slooff: "Co-expression of glial fibrillary acidic protein- and vimentin-type intermediate filaments in human astrocytomas." in: Acta neuropathologica, Vol. 70, Issue 3-4, pp. 333-9, 1986 (PubMed).

    Ramaekers, Puts, Moesker, Kant, Huysmans, Haag, Jap, Herman, Vooijs: "Antibodies to intermediate filament proteins in the immunohistochemical identification of human tumours: an overview." in: The Histochemical journal, Vol. 15, Issue 7, pp. 691-713, 1983 (PubMed).

  • Target
    GFAP
    Alternative Name
    Glial fibrillary acidic protein / GFAP (GFAP Antibody Abstract)
    Synonyms
    GFAP, AI836096, cb345, etID36982.3, gfapl, wu:fb34h11, wu:fk42c12, xx:af506734, zgc:110485, glial fibrillary acidic protein, GFAP, LOC100136168, gfap, Gfap
    Background
    GFAP (55 kD) is selectively located in astrocytes and represents the major constituent of astrocytic intermediate filaments. GFAP expression levels are highly variable during development of the central nervous system. In adults, GFAP levels increase as a result of the proliferation of astrocytes that occurs in a response to a variety of physical, chemical and etiological insults, including Alzheimer€™s disease, epilepsy and multiple sclerosis. In the peripheral nervous system GFAP is expressed by Schwann cells. Upon differentiation, myelin forming Schwann cells down-regulate GFAP, whereas in non-myelin forming Schwann cells GFAP persists into adulthood.
You are here:
help Support