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PDGFRB antibody (N-Term)

PDGFRB Reactivity: Human FACS, IF, IHC (p), WB Host: Rabbit Polyclonal RB01554 unconjugated
Catalog No. ABIN392034
$412.50
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  • Target See all PDGFRB Antibodies
    PDGFRB (Platelet Derived Growth Factor Receptor beta (PDGFRB))
    Binding Specificity
    • 22
    • 21
    • 21
    • 16
    • 15
    • 11
    • 8
    • 8
    • 7
    • 7
    • 6
    • 5
    • 5
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 40-72, N-Term
    Reactivity
    • 213
    • 93
    • 84
    • 5
    • 5
    • 5
    • 5
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 193
    • 29
    • 3
    • 2
    Rabbit
    Clonality
    • 183
    • 44
    Polyclonal
    Conjugate
    • 115
    • 14
    • 9
    • 9
    • 9
    • 7
    • 7
    • 7
    • 7
    • 7
    • 6
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 1
    • 1
    This PDGFRB antibody is un-conjugated
    Application
    • 123
    • 85
    • 58
    • 54
    • 53
    • 30
    • 29
    • 16
    • 16
    • 11
    • 9
    • 4
    • 2
    • 2
    • 1
    • 1
    Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
    Purification
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    Immunogen
    This PDGFRB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 40-72 amino acids from the N-terminal region of human PDGFRB.
    Clone
    RB01554
    Isotype
    Ig Fraction
  • Application Notes
    IF: 1:10~50. IHC-P: 1:10~50. FC: 1:10~50. WB: 1:1000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Expiry Date
    6 months
  • Target
    PDGFRB (Platelet Derived Growth Factor Receptor beta (PDGFRB))
    Alternative Name
    PDGFRB (PDGFRB Products)
    Synonyms
    AI528809, CD140b, PDGFR-1, Pdgfr, CD140B, IBGC4, JTK12, PDGFR, PDGFR1, platelet derived growth factor receptor, beta polypeptide, platelet derived growth factor receptor beta, Pdgfrb, PDGFRB
    Background
    PDGFRB is a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. The gene is flanked on chromosome 5 by the genes for granulocyte-macrophage colony-stimulating factor and macrophage-colony stimulating factor receptor, all three genes may be implicated in the 5-q syndrome. A translocation between chromosomes 5 and 12, that fuses the gene to that of the translocation, ETS, leukemia gene, results in chronic myelomonocytic leukemia.
    Molecular Weight
    123968
    Gene ID
    5159
    NCBI Accession
    NP_002600
    UniProt
    P09619
    Pathways
    Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Inositol Metabolic Process, Glycosaminoglycan Metabolic Process, Smooth Muscle Cell Migration, Platelet-derived growth Factor Receptor Signaling
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