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HOXB2 antibody (Homeobox B2) Primary Antibody

HOXB2 Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN499088
$513.70
Plus shipping costs $45.00
0.1 mg
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Available
  • Target
    HOXB2
    Reactivity
    • 13
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Human
    Host
    • 16
    Rabbit
    Clonality
    • 16
    Polyclonal
    Conjugate
    • 14
    • 1
    • 1
    This HOXB2 antibody is un-conjugated
    Application
    • 13
    • 8
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Specificity
    This antibody detects endogenous levels of HoxB2 protein. (region surrounding Pro67)
    Cross-Reactivity (Details)
    Species reactivity (tested):Human.
    Purification
    Affinity chromatography using epitope-specific immunogen
    Purity
    > 95 % (by SDS-PAGE)
  • Application Notes
    Western blot: 1: 500 - 1: 1000.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Concentration
    1.0 mg/mL
    Buffer
    Phosphate buffered saline (PBS), pH 7.2, 0.05 % sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
  • Target
    HOXB2
    Alternative Name
    HOXB2 / HOX2H (HOXB2 Antibody Abstract)
    Synonyms
    hox2, hox2h, hox-2.8, Hoxb-2, Z-151, hoxb2, hm:zehn0229, HOX2, HOX2H, Hox-2.8, K8, AI894218, Hoxbes2, homeobox B2, homeobox B2a, homeobox protein Hox-B2, HOXB2, hoxb2, hoxb2a, LOC733446, Hoxb2
    Background
    Hox genes play a fundamental role in the development of the vertebrate central nervous system, heart, axial skeleton, limbs, gut, urogenital tract and external genitalia. The homeobox gene HoxB1 is critical to hindbrain development and has phenotypic features frequently observed in autism. Analysis of expression and targeted disruption of HoxB1 demonstrates that it is also essential for patterning progenitor cells along the entire DV axis of rhombomere 4 (r4). HoxB1 maintains this function by acting very early during hindbrain neurogenesis to specify effectors of the Sonic hedgehog and Mash1 signaling pathways. HoxB2 is a homeodomain protein important in neural development that is also expressed during erythropoiesis, hindbrain development and normal human adult lung development. HoxB2 may modulate the amount of gamma-globin mRNA expressed during development and differentiation. In addition, HoxB2 plays an important role in the patterning of hindbrain and pharyngeal arches in the zebrafish.Synonyms: Homeobox protein Hox-B2, Hox-2.8, Hox-2H, K8
    Molecular Weight
    approx. 38 kDa
    Gene ID
    3212
    NCBI Accession
    NP_002136
    UniProt
    P14652
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