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PPP1R12B antibody (Middle Region)
PPP1R12B
Reactivity: Human
WB
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-PPP1R12B Antibody
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Target
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PPP1R12B
(Protein Phosphatase 1, Regulatory Subunit 12B (PPP1R12B))
Binding Specificity
All epitopes for PPP1R12B antibodies
Middle Region
Reactivity
All reactivities for PPP1R12B antibodies
Human
Host
All hosts for PPP1R12B antibodies
Rabbit
Clonality
All clonalities for PPP1R12B antibodies
Polyclonal
Conjugate
All conjugates for PPP1R12B antibodies
This PPP1R12B antibody is un-conjugated
Application
All applications for PPP1R12B antibodies
Western Blotting (WB)
Sequence
FNKPEEPKDE SPSSWRLGLR KTGSHNMLSE VANSREPIRD RGSSIYRSSS
Characteristics
This is a rabbit polyclonal antibody against MYPT2. It was validated on Western Blot.
Purification
Affinity purified
Immunogen
The immunogen for Anti-PPP1R12B antibody is: synthetic peptide directed towards the Middle region of Human MYPT2
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Target Details for PPP1R12B
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Target
PPP1R12B
(Protein Phosphatase 1, Regulatory Subunit 12B (PPP1R12B))
Alternative Name
PPP1R12B (PPP1R12B Products )
Synonyms
1810037O03Rik antibody, 9530009M10Rik antibody, AI132431 antibody, Mypt2 antibody, MYPT2 antibody, PP1bp55 antibody, protein phosphatase 1, regulatory subunit 12B antibody, protein phosphatase 1, regulatory (inhibitor) subunit 12B antibody, protein phosphatase 1 regulatory subunit 12B antibody, Ppp1r12b antibody, PPP1R12B antibody
Background
Myosin phosphatase is a protein complex comprised of three subunits: a catalytic subunit (PP1c-delta, protein phosphatase 1, catalytic subunit delta), a large regulatory subunit (MYPT, myosin phosphatase target) and small regulatory subunit (sm-M20). Two isoforms of MYPT have been isolated--MYPT1 and MYPT2, the first of which is widely expressed, and the second of which may be specific to heart, skeletal muscle, and brain. Each of the MYPT isoforms functions to bind PP1c-delta and increase phosphatase activity. This locus encodes both MYTP2 and M20. Alternatively spliced transcript variants encoding different isoforms have been identified. Related pseudogenes have been defined on the Y chromosome. Alias Symbols: MYPT2, PP1bp55 Protein Size: 982
Gene ID
4660
UniProt
O60237
Pathways
M Phase
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