Neuropilin 1 antibody (NRP1) (AA 22-644)

Details for Product anti-NRP1 Antibody No. ABIN5611190
Antigen
Epitope
AA 22-644
15
11
11
8
7
7
7
6
6
6
5
5
5
5
5
5
4
3
3
3
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
Reactivity
Human
162
102
89
4
3
2
2
1
1
1
1
1
1
1
1
Host
Mouse
175
33
9
4
Clonality (Clone)
Monoclonal ()
Conjugate
This Neuropilin 1 antibody is un-conjugated
23
16
9
7
5
4
4
4
4
4
3
2
2
1
1
1
1
1
1
1
1
Application
ELISA, Western Blotting (WB)
154
76
63
48
20
18
17
16
14
4
3
2
1
Options
Immunogen Purified recombinant fragment of human NRP1 (AA 22-644) expressed in HEK293 cells.
Clone 5H11G6
Isotype IgG1
Antigen
Alternative Name NRP1 (NRP1 Antibody Abstract)
Background This gene encodes one of two neuropilins, which contain specific protein domains which allow them to participate in several different types of signaling pathways that control cell migration. Neuropilins contain a large N-terminal extracellular domain, made up of complement-binding, coagulation factor V/VIII, and meprin domains. These proteins also contains a short membrane-spanning domain and a small cytoplasmic domain. Neuropilins bind many ligands and various types of co-receptors, they affect cell survival, migration, and attraction. Some of the ligands and co-receptors bound by neuropilins are vascular endothelial growth factor (VEGF) and semaphorin family members. Several alternatively spliced transcript variants that encode different protein isoforms have been described for this gene.
Molecular Weight 103.1kDa
HGNC 8829
Pathways Regulation of Cell Size, Signaling Events mediated by VEGFR1 and VEGFR2, Smooth Muscle Cell Migration, Platelet-derived growth Factor Receptor Signaling, VEGFR1 Specific Signals
Application Notes ELISA: 1:10000, WB: 1:500 - 1:2000, ICC: N:A, FCM: N:A, IHC: N:A
Restrictions For Research Use only
Format Liquid
Concentration 1.0 mg/mL
Buffer PBS with 0.05 % sodium azide
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C,-20 °C
Storage Comment 4°C, -20°C for long term storage
Supplier Images
Image no. 1 for anti-Neuropilin 1 (NRP1) (AA 22-644) antibody (ABIN5611190) Western blot analysis using NRP1 mAb against HEK293 (1) and NRP1 (AA: 22-644)-hIgGFc ...
Image no. 2 for anti-Neuropilin 1 (NRP1) (AA 22-644) antibody (ABIN5611190) Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen ...