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CCR5 antibody (Chemokine (C-C Motif) Receptor 5) Primary Antibody

CCR5 Reactivity: Human, Rat ELISA, FACS, IHC, WB Host: Mouse Monoclonal 6G11D1 unconjugated
Catalog No. ABIN5611203
$468.60
Plus shipping costs $45.00
0.1 mg
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  • Target See all CCR5 Antibodies
    CCR5
    Reactivity
    • 149
    • 45
    • 37
    • 13
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Rat
    Host
    • 103
    • 35
    • 17
    • 6
    • 1
    Mouse
    Clonality
    • 111
    • 48
    Monoclonal
    Conjugate
    • 81
    • 16
    • 11
    • 8
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CCR5 antibody is un-conjugated
    Application
    • 86
    • 65
    • 56
    • 25
    • 20
    • 20
    • 16
    • 14
    • 14
    • 6
    • 4
    • 3
    • 3
    • 1
    • 1
    ELISA, Flow Cytometry (FACS), Immunohistochemistry (IHC), Western Blotting (WB)
    Immunogen
    Purified recombinant fragment of human CD195 (AA extra mix) expressed in E. Coli.
    Clone
    6G11D1
    Isotype
    IgG1
  • Application Notes
    ELISA: 1:10000, WB: 1:500 - 1:2000, ICC: N:A, FCM: 1:200 - 1:400, IHC: 1:200 - 1:1000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1.0 mg/mL
    Buffer
    PBS with 0.05 % sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    4°C, -20°C for long term storage
  • Target
    CCR5
    Alternative Name
    CD195 (CCR5 Products)
    Synonyms
    CC-CKR-5, CCCKR5, CCR-5, CD195, CKR-5, CKR5, CMKBR5, IDDM22, Ckr5, Cmkbr5, CCR1-L, GPCR, CCR5, AM4-7, C-C motif chemokine receptor 5 (gene/pseudogene), chemokine (C-C motif) receptor 5, C-C motif chemokine receptor 5, CCR5, Ccr5
    Background
    This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. This protein is expressed by T cells and macrophages, and is known to be an important co-receptor for macrophage-tropic virus, including HIV, to enter host cells. Defective alleles of this gene have been associated with the HIV infection resistance. The ligands of this receptor include monocyte chemoattractant protein 2 (MCP-2), macrophage inflammatory protein 1 alpha (MIP-1 alpha), macrophage inflammatory protein 1 beta (MIP-1 beta) and regulated on activation normal T expressed and secreted protein (RANTES). Expression of this gene was also detected in a promyeloblastic cell line, suggesting that this protein may play a role in granulocyte lineage proliferation and differentiation. This gene is located at the chemokine receptor gene cluster region. An allelic polymorphism in this gene results in both functional and non-functional alleles, the reference genome represents the functional allele. Two transcript variants encoding the same protein have been found for this gene.
    Molecular Weight
    40.5kDa
    HGNC
    1234
    Pathways
    Cellular Response to Molecule of Bacterial Origin, cAMP Metabolic Process, Regulation of Cell Size
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