PCBD2 antibody (AA 31-130)

Catalog No. ABIN5675707

Product Details anti-PCBD2 Antibody

Target: PCBD2 (Pterin-4 alpha-Carbinolamine Dehydratase/dimerization Cofactor of Hepatocyte Nuclear Factor 1 alpha (TCF1) 2 (PCBD2))

Binding Specificity: AA 31-130

Reactivity: Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PCBD2 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)

Cross-Reactivity: Rat

Predicted Reactivity: Human,Mouse,Cow,Sheep,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human PCBD2

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for PCBD2

Target: PCBD2 (Pterin-4 alpha-Carbinolamine Dehydratase/dimerization Cofactor of Hepatocyte Nuclear Factor 1 alpha (TCF1) 2 (PCBD2))

Alternative Name: PCBD2 (PCBD2 Products)

Synonyms: 2700061N24Rik antibody, Dcoh2 antibody, Dcohm antibody, DCOH2 antibody, DCOHM antibody, PHS2 antibody, pterin 4 alpha carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (TCF1) 2 antibody, pterin-4 alpha-carbinolamine dehydratase 2 antibody, Pcbd2 antibody, PCBD2 antibody

Background:

Synonyms: Pterin-4-alpha-carbinolamine dehydratase 2, PCBD2, PHS 2, 4-alpha-hydroxy-tetrahydropterin dehydratase 2, DcoH-like protein DCoHm, Dimerization cofactor of hepatocyte nuclear factor 1 from muscle, HNF-1-alpha dimerization cofactor, PCBD2, DCOH2, DCOHM

Background: Involved in tetrahydrobiopterin biosynthesis. Seems to both prevent the formation of 7-pterins and accelerate the formation of quinonoid-BH2. Regulates the dimerization of homeodomain protein HNF-1-alpha and enhances its transcriptional activity.

Gene ID: 84105

UniProt: Q9H0N5