FGD5 antibody

Catalog No. ABIN5705610

Product Details anti-FGD5 Antibody

Target: FGD5 (FYVE, RhoGEF and PH Domain Containing 5 (FGD5))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FGD5 antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Immunogen: FYVE, RhoGEF and PH domain containing 5

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

mouse brain tissue were subjected to SDS PAGE followed by western blot with FNab03086(FGD5 antibody) at dilution of 1:500

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Expiry Date: 12 months

Target Details for FGD5

Target: FGD5 (FYVE, RhoGEF and PH Domain Containing 5 (FGD5))

Alternative Name: FGD5 (FGD5 Products)

Background: Synonyms:FGD5, ZFYVE23 Background:Activates CDC42, a member of the Ras-like family of Rho-and Rac proteins, by exchanging bound GDP for free GTP. Mediates VEGF-induced CDC42 activation. May regulate proangiogenic action of VEGF in vascular endothelial cells, including network formation, directional movement and proliferation. May play a role in regulating the actin cytoskeleton and cell shape.

Molecular Weight: 160 kDa

Gene ID: 152273

UniProt: Q6ZNL6