LRRC8C antibody

Catalog No. ABIN5705807

Product Details anti-LRRC8C Antibody

Target: LRRC8C (Leucine Rich Repeat Containing 8 Family, Member C (LRRC8C))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LRRC8C antibody is un-conjugated

Application: ELISA, Immunofluorescence (IF), Immunohistochemistry (IHC)

Immunogen: leucine rich repeat containing 8 family, member C

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Expiry Date: 12 months

Target Details for LRRC8C

Target: LRRC8C (Leucine Rich Repeat Containing 8 Family, Member C (LRRC8C))

Alternative Name: LRRC8C (LRRC8C Products)

Background: Synonyms:AD158, FAD158 Background:Non-essential component of the volume-regulated anion channel(VRAC, also named VSOAC channel), an anion channel required to maintain a constant cell volume in response to extracellular or intracellular osmotic changes. The VRAC channel conducts iodide better than chloride and may also conduct organic osmolytes like taurine. Channel activity requires LRRC8A plus at least one other family member(LRRC8B, LRRC8C, LRRC8D or LRRC8E), channel characteristics depend on the precise subunit composition.

Gene ID: 84230

UniProt: Q8TDW0