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TIMP2 antibody

TIMP2 Reactivity: Human, Rat, Mouse WB, IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN5963767
  • Target See all TIMP2 Antibodies
    TIMP2 (Metalloproteinase Inhibitor 2 (TIMP2))
    Reactivity
    • 115
    • 102
    • 70
    • 25
    • 24
    • 23
    • 21
    • 12
    • 12
    • 10
    • 10
    • 7
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    Human, Rat, Mouse
    Host
    • 121
    • 37
    • 8
    • 1
    • 1
    Rabbit
    Clonality
    • 121
    • 47
    Polyclonal
    Conjugate
    • 71
    • 17
    • 9
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This TIMP2 antibody is un-conjugated
    Application
    • 124
    • 46
    • 41
    • 40
    • 34
    • 29
    • 27
    • 13
    • 12
    • 12
    • 12
    • 9
    • 4
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF)
    Purification
    Affinity purification
    Immunogen
    A synthetic peptide of human TIMP2 (NP_003246.1).
    Isotype
    IgG
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  • Application Notes
    WB 1:500-1:2000 IF 1:50-1:200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    TIMP2 (Metalloproteinase Inhibitor 2 (TIMP2))
    Alternative Name
    TIMP2 (TIMP2 Products)
    Background
    This gene is a member of the TIMP gene family. The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases, a group of peptidases involved in degradation of the extracellular matrix. In addition to an inhibitory role against metalloproteinases, the encoded protein has a unique role among TIMP family members in its ability to directly suppress the proliferation of endothelial cells. As a result, the encoded protein may be critical to the maintenance of tissue homeostasis by suppressing the proliferation of quiescent tissues in response to angiogenic factors, and by inhibiting protease activity in tissues undergoing remodelling of the extracellular matrix.
    Molecular Weight

    Observed_MW: 22kDa

    Calculated_MW: 24kDa

    Gene ID
    7077
    UniProt
    P16035
    Pathways
    cAMP Metabolic Process
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