TIMP2 antibody
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- Target See all TIMP2 Antibodies
- TIMP2 (Metalloproteinase Inhibitor 2 (TIMP2))
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Reactivity
- Human, Rat, Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This TIMP2 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunofluorescence (IF)
- Purification
- Affinity purification
- Immunogen
- A synthetic peptide of human TIMP2 (NP_003246.1).
- Isotype
- IgG
- Top Product
- Discover our top product TIMP2 Primary Antibody
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- Application Notes
- WB 1:500-1:2000 IF 1:50-1:200
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- TIMP2 (Metalloproteinase Inhibitor 2 (TIMP2))
- Alternative Name
- TIMP2 (TIMP2 Products)
- Background
- This gene is a member of the TIMP gene family. The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases, a group of peptidases involved in degradation of the extracellular matrix. In addition to an inhibitory role against metalloproteinases, the encoded protein has a unique role among TIMP family members in its ability to directly suppress the proliferation of endothelial cells. As a result, the encoded protein may be critical to the maintenance of tissue homeostasis by suppressing the proliferation of quiescent tissues in response to angiogenic factors, and by inhibiting protease activity in tissues undergoing remodelling of the extracellular matrix.
- Molecular Weight
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Observed_MW: 22kDa
Calculated_MW: 24kDa
- Gene ID
- 7077
- UniProt
- P16035
- Pathways
- cAMP Metabolic Process
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