Ezrin (EZR) antibody

Details for Product No. ABIN5964745
Target
Reactivity
Human, Mouse, Rat
222
133
120
16
13
11
8
5
4
4
4
3
2
1
1
Host
Rabbit
184
27
9
2
1
Clonality
Polyclonal
Conjugate
Un-conjugated
13
9
8
8
8
8
8
6
6
3
3
3
3
3
2
1
1
1
Application
Immunohistochemistry (IHC), Western Blotting (WB)
153
71
53
39
37
24
22
12
12
3
2
2
2
1
1
Options
Immunogen Recombinant protein of human EZR
Isotype IgG
Purification Affinity purification
Target
Alternative Name EZR (EZR Antibody Abstract)
Background

Synonyms: Villin 2 ezrin,CVIL,CVL,Cytovillin 2,Cytovillin,DKFZp762H157,Epididymis secretory protein Li 105,EZR,EZRI,Ezrin,FLJ26216,HEL S 105,MGC1584,p81,VIL 2,VIL2,Villin 2 (ezrin),Villin 2,Villin-2,Villin2

Background: The cytoplasmic peripheral membrane protein encoded by this gene functions as a protein-tyrosine kinase substrate in microvilli. As a member of the ERM protein family, this protein serves as an intermediate between the plasma membrane and the actin cytoskeleton. This protein plays a key role in cell surface structure adhesion, migration and organization, and it has been implicated in various human cancers. A pseudogene located on chromosome 3 has been identified for this gene. Alternatively spliced variants have also been described for this gene.

Molecular Weight

Observed_MW: 90kDa

Calculated_MW: 69kDa

Gene ID 7430
UniProt P15311
Pathways Maintenance of Protein Location
Application Notes WB 1:500 - 1:2000 IHC 1:50 - 1:100
Restrictions For Research Use only
Concentration 1 mg/mL
Buffer Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store at -20°C. Avoid freeze / thaw cycles.
Images
Image no. 1 for anti-Ezrin (EZR) antibody (ABIN5964745) Western blot analysis of extracts of various cell lines, using EZR antibody.
Image no. 2 for anti-Ezrin (EZR) antibody (ABIN5964745) Immunohistochemistry of paraffin-embedded human stomach using EZR antibody.