GCLM antibody (AA 1-274)

Catalog No. ABIN6141019

Product Details anti-GCLM Antibody

Target: GCLM (Glutamate-Cysteine Ligase, Modifier Subunit (GCLM))

Binding Specificity: AA 1-274

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GCLM antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Sequence: MGTDSRAAKA LLARARTLHL QTGNLLNWGR LRKKCPSTHS EELHDCIQKT LNEWSSQINP DLVREFPDVL ECTVSHAVEK INPDEREEMK VSAKLFIVES NSSSSTRSAV DMACSVLGVA QLDSVIIASP PIEDGVNLSL EHLQPYWEEL ENLVQSKKIV AIGTSDLDKT QLEQLYQWAQ VKPNSNQVNL ASCCVMPPDL TAFAKQFDIQ LLTHNDPKEL LSEASFQEAL QESIPDIQAH EWVPLWLLRY SVIVKSRGII KSKGYILQAK RRGS

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-274 of human GCLM (NP_002052.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IF,1:50 - 1:200

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for GCLM

Target: GCLM (Glutamate-Cysteine Ligase, Modifier Subunit (GCLM))

Alternative Name: GCLM (GCLM Products)

Synonyms: Glclr antibody, GLCLR antibody, id:ibd3182 antibody, wu:fi24c07 antibody, zgc:55903 antibody, AI649393 antibody, Gcmc antibody, glutamate-cysteine ligase regulatory subunit antibody, glutamate cysteine ligase, modifier subunit antibody, glutamate-cysteine ligase modifier subunit antibody, glutamate-cysteine ligase, modifier subunit antibody, glutamate-cysteine ligase, modifier subunit L homeolog antibody, PTRG_09814 antibody, Gclm antibody, GCLM antibody, gclm antibody, gclm.L antibody

Background: Glutamate-cysteine ligase, also known as gamma-glutamylcysteine synthetase, is the first rate limiting enzyme of glutathione synthesis. The enzyme consists of two subunits, a heavy catalytic subunit and a light regulatory subunit. Gamma glutamylcysteine synthetase deficiency has been implicated in some forms of hemolytic anemia. Alternative splicing results in multiple transcript variants encoding different isoforms.,GCLM,GLCLR,Signal Transduction,Cell Biology & Developmental Biology,Apoptosis,Endocrine & Metabolism,Mitochondrial metabolism,Mitochondrial markers,Amino acid metabolism,Drug metabolism,Neuroscience,GCLM

Molecular Weight: 28 kDa/30 kDa

Gene ID: 2730

UniProt: P48507