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EPX antibody (Eosinophil Peroxidase) Primary Antibody

EPX Reactivity: Human FACS, IF Host: Mouse Monoclonal AHE-1 unconjugated
Catalog No. ABIN6173725
$306.46
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  • Target See all EPX Antibodies
    EPX
    Reactivity
    • 46
    • 5
    • 3
    • 1
    • 1
    • 1
    Human
    Host
    • 25
    • 21
    Mouse
    Clonality
    • 25
    • 21
    Monoclonal
    Conjugate
    • 18
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This EPX antibody is un-conjugated
    Application
    • 23
    • 21
    • 12
    • 9
    • 8
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    Flow Cytometry (FACS), Immunofluorescence (IF)
    Purpose
    Mouse Monoclonal anti-Eosinophil Peroxidase (AHE-1), Purified, with BSA
    Characteristics
    Peripheral blood granulocytes are classified into neutrophils, basophils and eosinophils according to the staining characteristics of their cytoplasmic granules. Granule proteins are released by physiologic and pharmacologic stimuli and play important roles in both normal and pathological host immune responses. Eosinophil major basic protein and eosinophil peroxidase (EPX) are granule proteins specific to the eosinophil. AHE-1 recognizes human EPX, a granule protein specific to eosinophils. It does not cross-react with eosinophil major basic protein, elastase, cathepsin G, esterase N, thrombin, plasmin, kallikrein, lactoferrin, or transferrin. This MAb stains eosinophils only and does not stain other peripheral blood cells, including platelets, neutrophils, monocytes, lymphocytes or red blood cells. Human EPX gene product can form a tetramer of two light chains and two heavy chains. Other peroxidase family members include myeloperoxidase (MPO), lactoperoxidase (LPO), and thyroid peroxidase (TPO). Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
    Purification
    Purified
    Immunogen
    Human eosinophils from a patient with hypereosinophilic syndrome
    Clone
    AHE-1
    Isotype
    IgG1 kappa
  • Application Notes
    Immunofluorescence 0.5-1 μg/mL
    • Flow Cytometry 0.5-1 μg/million cells/0.1 mL
    • Optimal dilution for a specific application should be determined by user
    Comment

    MCF-7 cells. Tonsil

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    200 μg/mL
    Buffer
    PBS/0.05 % BSA/0.05 % azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Target
    EPX
    Alternative Name
    Eosinophil Peroxidase (EPX Products)
    Synonyms
    EPX, pmr-1, EPO, EPP, EPX-PEN, eosinophil peroxidase, eosinophil peroxidase L homeolog, LOC788751, EPX, epx.L, Epx
    Background
    Eosinophil peroxidase heavy chain, EPER, EPO, EPP, EPX, EPX PEN, PERE
    Molecular Weight
    70 kDa (55 kDa-Heavy Chain, 15 kDa-Light Chain)
    Gene ID
    8288, 279259
    UniProt
    P11678
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