DAZAP2 antibody

Catalog No. ABIN6290277

Product Details anti-DAZAP2 Antibody

Target: DAZAP2 (DAZ Associated Protein 2 (DAZAP2))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DAZAP2 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Affinity purification

Immunogen: Recombinant protein of human DAZAP2

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000

Comment:

Widely expressed, Expressed in spleen, thymus, prostate, testis, ovary, small intestine, colon and leukocytes, Down-regulated in multiple myeloma

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20C. Avoid freeze / thaw cycles.

Target Details for DAZAP2

Target: DAZAP2 (DAZ Associated Protein 2 (DAZAP2))

Alternative Name: DAZAP2 (DAZAP2 Products)

Background: This gene encodes a proline-rich protein which interacts with the deleted in azoospermia (DAZ) and the deleted in azoospermia-like gene through the DAZ-like repeats. This protein also interacts with the transforming growth factor-beta signaling molecule SARA (Smad anchor for receptor activation), eukaryotic initiation factor 4G, and an E3 ubiquitinase that regulates its stability in splicing factor containing nuclear speckles. The encoded protein may function in various biological and pathological processes including spermatogenesis, cell signaling and transcription regulation, formation of stress granules during translation arrest, RNA splicing, and pathogenesis of multiple myeloma. Multiple transcript variants encoding different isoforms have been found for this gene.

Molecular Weight: 17.319 kDa

Gene ID: 9802

UniProt: Q15038