p63 antibody (Tumor Protein P63)

Details for Product anti-TP63 Antibody No. ABIN6297602
Antigen
  • AIS
  • B(p51A)
  • B(p51B)
  • EEC3
  • KET
  • LMS
  • NBP
  • OFC8
  • RHS
  • SHFM4
  • TP53CP
  • TP53L
  • TP73L
  • p40
  • p51
  • p53CP
  • p63
  • p73H
  • p73L
  • TP63
  • tp63
  • DNp63
  • id:ibd3516
  • tp73l
  • wu:fc89f04
  • wu:fk85h07
  • wu:fk88b02
  • Ket
  • P73l
  • Tp73l
  • Trp63
  • TRP63
  • AI462811
  • P51/P63
  • P63
  • Tp63
  • Trp53rp1
  • Xp63
  • ket
  • np63
  • tp73l-A
  • trp63
  • tumor protein p63
  • transformation related protein 63
  • tumor protein p63 L homeolog
  • TP63
  • tp63
  • Tp63
  • Trp63
  • tp63.L
Reactivity
Human
121
42
32
4
2
Host
Rabbit
76
47
2
Clonality
Polyclonal
Conjugate
This p63 antibody is un-conjugated
2
1
1
1
1
1
1
1
1
1
1
1
Application
Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (IHC)
77
56
34
20
16
14
9
8
8
5
4
4
2
1
Options
Purpose Rabbit anti-Human p63 Antibody / Tumor protein 63 [Sodium Azide Free]
Immunogen Recombinant partial human p53 protein was used as the immunogen for this p63 antibody.
Specificity Nuclear
Purification Recombinant partial human p53 protein was used as the immunogen for this p63 antibody.
Plasmids, Primers & others Plasmids, Primers & others p63 products on genomics-online (e.g. as negative or positive controls)
Antigen
Alternative Name Tumor protein 63 (TP63 Antibody Abstract)
Background

Target Description: p63 is a homolog of the tumor suppressor p53. It is identified in basal cells in the epithelial layers of a variety of tissues, including epidermis, cervix, urothelium, breast and prostate. p63 was detected in nuclei of the basal epithelium in normal prostate glands, however, it was not expressed in malignant tumors of the prostate. As a result, p63 has been reported as a useful marker for differentiating benign from malignant lesions in the prostate, particularly when used in combination with markers of high molecular weight cytokeratins and the prostate-specific marker AMACR (P504S). p63 has also been shown to be a sensitive marker for lung squamous cell carcinomas (SqCC), with a sensitivity of ~90 % . Specificity for lung SqCC, vs. lung adenocarcinoma (LADC), is approximately 80 %. In breast tissue, p63 has been identified in myoepithelial cells of normal ducts.

Gene Symbol: TP63///KET///P63///P73H///P73L///TP73L
Gene ID 8626
UniProt Q9H3D4
Application Notes Flow Cytometry: 0.5-1 μg/million cells in 0.1ml
Immunofluorescence: 1-2 μg/mL
Immunohistochemistry (FFPE): 1-2 μg/mL for 30 minutes at RT
Restrictions For Research Use only
Buffer In 1X PBS, BSA free, sodium azide free
Preservative Azide free
Storage 4 °C,-20 °C
Storage Comment 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
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