CD1b antibody (CD1b Molecule)

Details for Product anti-CD1B Antibody No. ABIN6297677
Antigen
  • CD1
  • CD1A
  • R1
  • CD1B3
  • CD1B
  • CD1-b
  • CD1b molecule
  • T-cell surface glycoprotein CD1b-3
  • CD1b1 molecule
  • T-cell surface glycoprotein CD1b1
  • CD1B
  • LOC443423
  • CD1B1
  • LOC100720602
Reactivity
Human
158
7
7
2
2
2
2
2
Host
Mouse
103
56
Clonality
Monoclonal
Conjugate
This CD1b antibody is un-conjugated
9
9
7
4
4
4
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
Application
Flow Cytometry (FACS), Functional Studies (Func), Immunofluorescence (IF)
94
57
51
32
19
17
13
9
8
3
2
Options
Purpose Mouse anti-Human CD1b Antibody [Sodium Azide Free]
Immunogen Stimulated human leukocytes were used as the immunogen for the CD1b antibody.
Specificity Cell surface
Purification Stimulated human leukocytes were used as the immunogen for the CD1b antibody.
Plasmids, Primers & others Plasmids, Primers & others CD1b products on genomics-online (e.g. as negative or positive controls)
Antigen
Alternative Name T-cell surface glycoprotein CD1b (CD1B Antibody Abstract)
Background

Target Description: The mouse monoclonal antibody recognizes CD1b, a 44 kDa type I glycoprotein associated with beta2-microglobulin (Workshop IV, Code T015). It is expressed on dendritic cells, Langerhans cells, thymocytes, and T acute lymphoblastic leukemia cells. The CD1 multigene family encodes five forms of the CD1 T-cell surface glycoprotein in human, designated CD1A, 1B, 1C, 1D and 1E. CD1, a type 1 membrane protein, has structural similarity to the MHC class I antigen and has been shown to present lipid antigens for recognition by T lymphocytes. Constitutive endocytosis of CD1B molecules and the differential sorting of MHC class II from lysosomes separate peptide- and lipid antigen-presenting molecules during dendritic cell maturation. CD1B is also expressed in interdigitating cells.

Gene Symbol: CD1B

Gene ID 910
UniProt P29016
Application Notes Flow Cytometry: 0.5-1 μg/million cells in 0.1ml
Immunofluorescence: 0.5-1 μg/mL
Functional Activity (Order SAF formulation)
Restrictions For Research Use only
Buffer In 1X PBS, BSA free, sodium azide free
Preservative Azide free
Storage 4 °C,-20 °C
Storage Comment 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
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