CD5 antibody (CD5 Molecule)

Details for Product anti-CD5 Antibody No. ABIN6297702
Antigen
  • CD5
  • Ly-1
  • Ly-12
  • Ly-A
  • Lyt-1
  • LEU1
  • T1
  • CD5 molecule
  • CD5 antigen
  • CD5 molecule like
  • Cd5 molecule
  • CD5
  • Cd5
  • CD5L
Reactivity
Human, Rhesus Monkey
676
248
149
63
58
44
38
37
35
32
29
29
21
5
2
2
1
1
Host
Mouse
683
168
149
Clonality
Monoclonal
Conjugate
This CD5 antibody is un-conjugated
134
119
78
67
18
14
10
9
9
9
8
7
4
4
4
4
4
4
4
4
4
4
4
4
4
4
4
4
4
3
3
3
2
2
2
1
1
1
1
1
1
Application
Flow Cytometry (FACS), Functional Studies (Func), Immunofluorescence (IF)
753
234
205
166
164
115
77
69
68
24
14
14
13
13
12
11
4
3
2
2
1
1
1
Options
Purpose Mouse anti-Human/Rhesus Monkey. CD5 Antibody [Sodium Azide Free]
Immunogen Stimulated human leukocytes were used as the immunogen for this CD5 antibody.
Specificity Cell surface
Purification Stimulated human leukocytes were used as the immunogen for this CD5 antibody.
Plasmids, Primers & others Plasmids, Primers & others CD5 products on genomics-online (e.g. as negative or positive controls)
Antigen
Alternative Name T-cell surface glycoprotein CD5 (CD5 Antibody Abstract)
Background

Target Description: This antibody recognizes a 67 kDa transmembrane protein, which is identified as CD5. It is found on 95 % of thymocytes and 72 % of peripheral blood lymphocytes. In lymph nodes, the main reactivity is observed in Tcell areas. CD5 antibody is a pan Tcell marker that also reacts with a range of neoplastic Bcells, e.g. chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL), mantle cell lymphoma, and a subset (~10 %) of diffuse large Bcell lymphoma. Aberrant expression is useful in making a diagnosis of mature Tcell neoplasms. CD5 antibody detection is diagnostic in CLL/SLL within a panel of other Bcell markers, especially one that includes anti-CD23. CD5 antibody is also very useful in differentiating among mature small lymphoid cell malignancies. In addition, it can be used in distinguishing thymic carcinoma (+) from thymoma (-). It does not react with granulocytes or monocytes.

Gene Symbol: CD5///LEU1

Gene ID 921
UniProt P06127
Application Notes Functional Testing: order BSA/azide-free format
FACS: 0.5-1 μg/million cells
IF: 0.5-1 μg/mL
Restrictions For Research Use only
Buffer In 1X PBS ( pH 7.4), BSA free, sodium azide free
Preservative Azide free
Storage 4 °C,-20 °C
Storage Comment 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.