CD5 antibody
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- Target See all CD5 Antibodies
- CD5
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Reactivity
- Human, Rhesus Monkey
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This CD5 antibody is un-conjugated
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Application
- Flow Cytometry (FACS), Immunofluorescence (IF), Functional Studies (Func)
- Purpose
- Mouse anti-Human/Rhesus Monkey. CD5 Antibody [Sodium Azide Free]
- Specificity
- Cell surface
- Purification
- Stimulated human leukocytes were used as the immunogen for this CD5 antibody.
- Immunogen
- Stimulated human leukocytes were used as the immunogen for this CD5 antibody.
- Top Product
- Discover our top product CD5 Primary Antibody
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- Application Notes
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Functional Testing: order BSA/azide-free format
FACS: 0.5-1 μg/million cells
IF: 0.5-1 μg/mL - Restrictions
- For Research Use only
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- Buffer
- In 1X PBS ( pH 7.4), BSA free, sodium azide free
- Preservative
- Azide free
- Storage
- 4 °C,-20 °C
- Storage Comment
- 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
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- Target
- CD5
- Alternative Name
- T-cell surface glycoprotein CD5 (CD5 Products)
- Synonyms
- CD5 antibody, Ly-1 antibody, Ly-12 antibody, Ly-A antibody, Lyt-1 antibody, LEU1 antibody, T1 antibody, CD5 molecule antibody, CD5 antigen antibody, CD5 molecule like antibody, Cd5 molecule antibody, CD5 antibody, Cd5 antibody, CD5L antibody
- Background
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Target Description: This antibody recognizes a 67 kDa transmembrane protein, which is identified as CD5. It is found on 95 % of thymocytes and 72 % of peripheral blood lymphocytes. In lymph nodes, the main reactivity is observed in Tcell areas. CD5 antibody is a pan Tcell marker that also reacts with a range of neoplastic Bcells, e.g. chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL), mantle cell lymphoma, and a subset (~10 %) of diffuse large Bcell lymphoma. Aberrant expression is useful in making a diagnosis of mature Tcell neoplasms. CD5 antibody detection is diagnostic in CLL/SLL within a panel of other Bcell markers, especially one that includes anti-CD23. CD5 antibody is also very useful in differentiating among mature small lymphoid cell malignancies. In addition, it can be used in distinguishing thymic carcinoma (+) from thymoma (-). It does not react with granulocytes or monocytes.
Gene Symbol: CD5///LEU1
- Gene ID
- 921
- UniProt
- P06127
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