CD6 antibody (CD6)

Details for Product anti-CD6 Antibody No. ABIN6297741
Target
Reactivity
Human
127
32
27
2
2
1
1
Host
Mouse
98
51
2
Clonality
Monoclonal
Conjugate
This CD6 antibody is un-conjugated
12
11
8
5
3
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
Application
Immunohistochemistry (IHC)
99
59
55
37
32
21
18
17
13
6
5
4
4
2
Options
Purpose Mouse anti-Human CD6 Antibody [IHC only]
Immunogen The human rheumatoid synovial T cell line ST-1 was used as the immunogen for this CD6 antibody.
Specificity Cell surface and cytoplasmic
Purification The human rheumatoid synovial T cell line ST-1 was used as the immunogen for this CD6 antibody.
Target
Alternative Name T-cell differentiation antigen CD6 (CD6 Antibody Abstract)
Background

Target Description: CD6 is a type I transmembrane glycoprotein that contains a 24-amino acid signal sequence, three extracellular ""scavenger receptor cysteine-rich "" (SRCR) domains, a membrane-spanning domain and a 44-amino acid cytoplasmic domain. The glycoprotein is tyrosine phosphorylated during TCR-mediated T cell activation. It shows significant homology to CD5. CD6 is present on mature thymocytes, peripheral T cells and a subset of B cells. CD6 antibody can be used to deplete T cells from bone marrow transplants to prevent graft versus host disease.

Gene Symbol: CD6

Gene ID 923
UniProt P30203
Application Notes Prediluted format : incubate for 30 min at RT (2)
Restrictions For Research Use only
Buffer Prediluted in 1X PBS ( pH 7.4) with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide, For IHC use only
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C,-20 °C
Storage Comment 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.