CD6 antibody (CD6)

Details for Product anti-CD6 Antibody No. ABIN6297742
Antigen
  • TP120
  • OX52
  • CD6 antigen
  • CD6 molecule
  • Cd6 molecule
  • Cd6
  • CD6
Reactivity
Human
281
37
32
6
3
2
2
Host
Mouse
234
81
4
Clonality
Monoclonal
Conjugate
This CD6 antibody is un-conjugated
21
18
18
10
7
6
5
3
3
3
3
3
3
3
3
3
3
3
3
3
3
2
2
2
2
2
2
1
1
1
1
1
Application
Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (IHC)
214
118
118
81
63
51
50
41
13
10
10
7
5
5
Options
Purpose Mouse anti-Human CD6 Antibody [Sodium Azide Free]
Immunogen The human rheumatoid synovial T cell line ST-1 was used as the immunogen for this CD6 antibody.
Specificity Cell surface and cytoplasmic
Purification The human rheumatoid synovial T cell line ST-1 was used as the immunogen for this CD6 antibody.
Antigen
Alternative Name T-cell differentiation antigen CD6 (CD6 Antibody Abstract)
Background

Target Description: CD6 is a type I transmembrane glycoprotein that contains a 24-amino acid signal sequence, three extracellular ""scavenger receptor cysteine-rich "" (SRCR) domains, a membrane-spanning domain and a 44-amino acid cytoplasmic domain. The glycoprotein is tyrosine phosphorylated during TCR-mediated T cell activation. It shows significant homology to CD5. CD6 is present on mature thymocytes, peripheral T cells and a subset of B cells. CD6 antibody can be used to deplete T cells from bone marrow transplants to prevent graft versus host disease.

Gene Symbol: CD6

Gene ID 923
UniProt P30203
Application Notes FACS: 0.5-1 μg/million cells
IF: 0.5-1 μg/mL
IHC (FFPE): 0.5-1 μg/mL for 30 minutes at RT (1)
Prediluted format: incubate for 30 min at RT (2)
Restrictions For Research Use only
Buffer In 1X PBS ( pH 7.4), BSA free, sodium azide free
Preservative Azide free
Storage 4 °C,-20 °C
Storage Comment 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.