CD70 antibody

Catalog No. ABIN6297746

Product Details anti-CD70 Antibody

Target: CD70 (CD70 Molecule (CD70))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD70 antibody is un-conjugated

Application: ELISA, Flow Cytometry (FACS), Immunofluorescence (IF), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro)), Proliferation Assay (ProA), Functional Studies (Func)

Purpose: Mouse anti-Human CD70 Antibody [Sodium Azide Free]

Specificity: Cell surface

Purification: The human WM-1 (Waldenstrom s macroglobulinemia) cell line was used as the immunogen for the CD70 antibody.

Immunogen: The human WM-1 (Waldenstrom s macroglobulinemia) cell line was used as the immunogen for the CD70 antibody.

Application Details

Application Notes: ELISA (order Ab without BSA)
Functional Activity: Inhibits T cell proliferation induced by dendritic cells (Order SAF formulation) (1)
Flow Cytometry: 0.5-1 μg/million cells in 0.1ml
Immunofluorescence: 0.5-1 μg/mL
Immunoprecipitation: 0.5-1 μg/500 μg protein lysate
Immunohistochemistry (Frozen): 0.5-1 μg/mL for 30 min at RT

Restrictions: For Research Use only

Handling

Buffer: In 1X PBS, BSA free, sodium azide free

Preservative: Azide free

Storage: 4 °C,-20 °C

Storage Comment: 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.

Target Details for CD70

Target: CD70 (CD70 Molecule (CD70))

Alternative Name: CD70 antigen (CD70 Products)

Background:

Target Description: CD70 belongs to the tumor necrosis factor (TNF) ligand family. It is a cytokine that binds to CD27. Plays a role in T-cell activation. Induces the proliferation of costimulated T-cells and enhances the generation of cytolytic T-cells.

Gene Symbol: CD70///CD27L///CD27LG///TNFSF7

Gene ID: 970

UniProt: P32970

Pathways: Cancer Immune Checkpoints