CD70 antibody (CD70 Molecule)

Details for Product anti-CD70 Antibody No. ABIN6297746
Antigen
  • CD27LG
  • Cd27l
  • Tnfsf7
  • CD27L
  • TNFSF7
  • CD70 antigen
  • CD70 molecule
  • Cd70 molecule
  • Cd70
  • CD70
Reactivity
Human
213
31
9
3
3
2
2
2
2
1
1
Host
Mouse
109
105
14
3
1
Clonality
Monoclonal
Conjugate
This CD70 antibody is un-conjugated
17
16
13
6
5
4
3
3
3
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
Application
ELISA, Flow Cytometry (FACS), Functional Studies (Func), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunoprecipitation (IP), Proliferation Assay (ProA)
108
100
77
70
68
67
62
46
23
22
21
14
6
5
4
2
2
2
1
1
Options
Purpose Mouse anti-Human CD70 Antibody [Sodium Azide Free]
Immunogen The human WM-1 (Waldenstrom s macroglobulinemia) cell line was used as the immunogen for the CD70 antibody.
Specificity Cell surface
Purification The human WM-1 (Waldenstrom s macroglobulinemia) cell line was used as the immunogen for the CD70 antibody.
Plasmids, Primers & others Plasmids, Primers & others CD70 products on genomics-online (e.g. as negative or positive controls)
Antigen
Alternative Name CD70 antigen (CD70 Antibody Abstract)
Background

Target Description: CD70 belongs to the tumor necrosis factor (TNF) ligand family. It is a cytokine that binds to CD27. Plays a role in T-cell activation. Induces the proliferation of costimulated T-cells and enhances the generation of cytolytic T-cells.

Gene Symbol: CD70///CD27L///CD27LG///TNFSF7
Gene ID 970
UniProt P32970
Pathways Cancer Immune Checkpoints
Application Notes ELISA (order Ab without BSA)
Functional Activity: Inhibits T cell proliferation induced by dendritic cells (Order SAF formulation) (1)
Flow Cytometry: 0.5-1 μg/million cells in 0.1ml
Immunofluorescence: 0.5-1 μg/mL
Immunoprecipitation: 0.5-1 μg/500 μg protein lysate
Immunohistochemistry (Frozen): 0.5-1 μg/mL for 30 min at RT
Restrictions For Research Use only
Buffer In 1X PBS, BSA free, sodium azide free
Preservative Azide free
Storage 4 °C,-20 °C
Storage Comment 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.