Thyroglobulin antibody (TG)

Details for Product anti-TG Antibody No. ABIN6297748
Antigen
  • TG
  • cb717
  • AITD3
  • TGN
  • Tgn
  • cog
  • thyroglobulin
  • TG
  • tg
  • LOC701526
  • LOC701756
  • LOC100434297
  • Tg
Reactivity
Human, Mouse (Murine), Rat (Rattus)
416
132
132
6
2
1
1
1
1
Host
Mouse
341
76
9
3
1
Clonality
Monoclonal
Conjugate
This Thyroglobulin antibody is un-conjugated
15
9
8
7
7
6
5
4
4
4
4
4
4
4
4
4
4
4
4
4
1
1
1
1
1
1
Application
Immunohistochemistry (IHC)
151
138
133
114
88
84
24
17
16
13
12
11
9
8
6
4
2
2
2
2
2
2
1
Options
Purpose Mouse anti-Human/Mouse/Rat Thyroglobulin Antibody [IHC only]
Immunogen The immunogen for this Thyroglobulin antibody was human thyroid epithelial cells.
Specificity Cytoplasmic and secreted
Purification The immunogen for this Thyroglobulin antibody was human thyroid epithelial cells.
Plasmids, Primers & others Plasmids, Primers & others Thyroglobulin products on genomics-online (e.g. as negative or positive controls)
Antigen
Alternative Name Thyroglobulin (TG Antibody Abstract)
Background

Target Description: Thyroglobulin (Tg) is a glycoprotein homodimer produced predominantly by the thryroid gland. It acts as a substrate for the synthesis of thyroxine and triiodothyronine as well as the storage of the inactive forms of thyroid hormone and iodine. Thyroglobulin is secreted from the endoplasmic reticulum to its site of iodination, and subsequent thyroxine biosynthesis, in the follicular lumen. Mutations in this gene cause thyroid dyshormonogenesis, manifested as goiter, and are associated with moderate to severe congenital hypothyroidism. Polymorphisms in this gene are associated with susceptibility to autoimmune thyroid diseases (AITD) such as Graves disease and Hashimoto thryoiditis. [provided by RefSeq]

Gene Symbol: TG

Gene ID 7038
UniProt P01266
Pathways Thyroid Hormone Synthesis
Application Notes Prediluted format : incubate for 30 min at RT (2)
Restrictions For Research Use only
Buffer Prediluted in 1X PBS ( pH 7.4) with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide, For IHC use only
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C,-20 °C
Storage Comment 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
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