Thyroglobulin antibody
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- Target See all Thyroglobulin (TG) Antibodies
- Thyroglobulin (TG)
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Reactivity
- Human, Mouse, Rat
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This Thyroglobulin antibody is un-conjugated
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Application
- Immunohistochemistry (IHC)
- Purpose
- Mouse anti-Human/Mouse/Rat Thyroglobulin Antibody [IHC only]
- Specificity
- Cytoplasmic and secreted
- Purification
- The immunogen for this Thyroglobulin antibody was human thyroid epithelial cells.
- Immunogen
- The immunogen for this Thyroglobulin antibody was human thyroid epithelial cells.
- Top Product
- Discover our top product TG Primary Antibody
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- Application Notes
- Prediluted format : incubate for 30 min at RT (2)
- Restrictions
- For Research Use only
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- Buffer
- Prediluted in 1X PBS ( pH 7.4) with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide, For IHC use only
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
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- Target
- Thyroglobulin (TG)
- Alternative Name
- Thyroglobulin (TG Products)
- Synonyms
- TG antibody, cb717 antibody, AITD3 antibody, TGN antibody, Tgn antibody, cog antibody, thyroglobulin antibody, TG antibody, tg antibody, LOC701526 antibody, LOC701756 antibody, LOC100434297 antibody, Tg antibody
- Background
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Target Description: Thyroglobulin (Tg) is a glycoprotein homodimer produced predominantly by the thryroid gland. It acts as a substrate for the synthesis of thyroxine and triiodothyronine as well as the storage of the inactive forms of thyroid hormone and iodine. Thyroglobulin is secreted from the endoplasmic reticulum to its site of iodination, and subsequent thyroxine biosynthesis, in the follicular lumen. Mutations in this gene cause thyroid dyshormonogenesis, manifested as goiter, and are associated with moderate to severe congenital hypothyroidism. Polymorphisms in this gene are associated with susceptibility to autoimmune thyroid diseases (AITD) such as Graves disease and Hashimoto thryoiditis. [provided by RefSeq]
Gene Symbol: TG
- Gene ID
- 7038
- UniProt
- P01266
- Pathways
- Thyroid Hormone Synthesis
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