Retinoic Acid Receptor alpha antibody (Retinoic Acid Receptor, alpha)

Details for Product anti-RARA Antibody No. ABIN6566584
Antigen
Reactivity
Human, Mouse (Murine), Rat (Rattus)
180
95
77
7
6
4
3
2
2
1
1
1
Host
Rabbit
129
51
7
Clonality
Polyclonal
Conjugate
This Retinoic Acid Receptor alpha antibody is un-conjugated
7
4
4
4
4
4
4
4
4
3
3
3
1
1
1
1
1
Application
Immunohistochemistry (IHC), Western Blotting (WB)
156
87
76
32
23
19
15
13
5
4
3
2
2
2
2
2
1
1
Options
Immunogen Recombinant protein of human RARA
Isotype IgG
Purification Affinity purification
Antigen
Alternative Name RARA (RARA Antibody Abstract)
Background

Synonyms: NR1B1,Nuclear mitotic apparatus protein retinoic acid receptor alpha fusion protein,Nuclear receptor subfamily 1 group B member 1,Nucleophosmin retinoic acid receptor alpha fusion protein NPM RAR long form,RAR alpha,RAR,RAR-alpha,rara,RARA,RARalpha,RARalpha1,Retinoic acid nuclear receptor alpha variant 1,Retinoic acid nuclear receptor alpha variant 2,Retinoic acid receptor alpha,Retinoic acid receptor alpha polypeptide

Background: This gene represents a nuclear retinoic acid receptor. The encoded protein, retinoic acid receptor alpha, regulates transcription in a ligand-dependent manner. This gene has been implicated in regulation of development, differentiation, apoptosis, granulopoeisis, and transcription of clock genes. Translocations between this locus and several other loci have been associated with acute promyelocytic leukemia. Alternatively spliced transcript variants have been found for this locus.

Molecular Weight

Observed_MW: 51kDa

Calculated_MW: 39kDa/50kDa

Gene ID 5914
UniProt P10276
Pathways Nuclear Receptor Transcription Pathway, Retinoic Acid Receptor Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process
Application Notes WB 1:500 - 1:2000 IHC 1:50 - 1:100
Restrictions For Research Use only
Concentration 1 mg/mL
Buffer Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store at -20°C. Avoid freeze / thaw cycles.
Supplier Images
Image no. 1 for anti-Retinoic Acid Receptor, alpha (RARA) antibody (ABIN6566584) Western blot analysis of extracts of various cell lines, using RARA antibody.
Image no. 2 for anti-Retinoic Acid Receptor, alpha (RARA) antibody (ABIN6566584) Immunohistochemistry of paraffin-embedded rat lung using RARA antibody.