NUMA1 antibody (Nuclear Mitotic Apparatus Protein 1)

Details for Product anti-NUMA1 Antibody No. ABIN6566605
Antigen
Reactivity
Human, Mouse (Murine), Rat (Rattus)
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46
27
3
3
2
2
1
1
1
1
1
1
Host
Rabbit
101
43
Clonality
Polyclonal
Conjugate
This NUMA1 antibody is un-conjugated
7
5
5
5
5
5
5
3
3
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (IHC), Western Blotting (WB)
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43
36
33
28
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26
16
9
7
4
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2
1
1
Options
Immunogen Recombinant protein of human NUMA1
Isotype IgG
Purification Affinity purification
Antigen
Alternative Name NUMA1
Background

Synonyms: Centrophilin stabilizes mitotic spindle in mitotic cells,NMP 22,Nuclear matrix protein 22,Nuclear mitotic apparatus protein 1,Nuclear mitotic apparatus protein,NUMA 1,NUMA,NuMA protein,NUMA1,NUMA1,SP H antigen,SP-H antigen,Structural nuclear protein

Background: This gene encodes a large protein that forms a structural component of the nuclear matrix. The encoded protein interacts with microtubules and plays a role in the formation and organization of the mitotic spindle during cell division. Chromosomal translocation of this gene with the RARA (retinoic acid receptor, alpha) gene on chromosome 17 have been detected in patients with acute promyelocytic leukemia. Alternative splicing results in multiple transcript variants.

Molecular Weight

Observed_MW: 238kDa

Calculated_MW: 109kDa/200kDa/201kDa/236kDa/238kDa

Gene ID 4926
UniProt Q14980
Pathways Caspase Cascade in Apoptosis, Regulation of Actin Filament Polymerization, M Phase
Application Notes WB 1:200 - 1:1000 IHC 1:50 - 1:100
Restrictions For Research Use only
Concentration 1 mg/mL
Buffer Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store at -20°C. Avoid freeze / thaw cycles.
Supplier Images
Image no. 1 for anti-Nuclear Mitotic Apparatus Protein 1 (NUMA1) antibody (ABIN6566605) Western blot analysis of extracts of various cell lines, using NUMA1 antibody.
Image no. 2 for anti-Nuclear Mitotic Apparatus Protein 1 (NUMA1) antibody (ABIN6566605) Immunohistochemistry of paraffin-embedded human stomach using NUMA1 antibody.
Image no. 3 for anti-Nuclear Mitotic Apparatus Protein 1 (NUMA1) antibody (ABIN6566605) Immunohistochemistry of paraffin-embedded rat heart using NUMA1 antibody.
Image no. 4 for anti-Nuclear Mitotic Apparatus Protein 1 (NUMA1) antibody (ABIN6566605) Immunohistochemistry of paraffin-embedded mouse stomach using NUMA1 antibody.