Dystroglycan antibody (Dystroglycan 1)

Details for Product anti-DAG1 Antibody No. ABIN6566766
Antigen
Reactivity
Human, Mouse (Murine), Rat (Rattus)
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2
2
2
1
1
1
1
1
Host
Rabbit
63
10
7
2
Clonality
Polyclonal
Conjugate
This Dystroglycan antibody is un-conjugated
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4
4
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3
3
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2
2
1
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1
Application
Western Blotting (WB)
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Options
Immunogen Recombinant protein of human DAG1
Isotype IgG
Purification Affinity purification
Antigen
Alternative Name DAG1 (DAG1 Antibody Abstract)
Background

Synonyms: 156DAG,A3a,AGRNR,Alpha dystroglycan,Alpha-DG,Beta-DG,Beta-dystroglycan,DAG,Dag1,DAG1,Dystroglycan 1 (dystrophin associated glycoprotein 1),Dystroglycan,Dystrophin associated glycoprotein 1,Dystrophin-associated glycoprotein 1,OTTHUMP00000210857,OTTHUMP00000210858

Background: This gene encodes dystroglycan, a central component of dystrophin-glycoprotein complex that links the extracellular matrix and the cytoskeleton in the skeletal muscle. The encoded preproprotein undergoes O- and N-glycosylation, and proteolytic processing to generate alpha and beta subunits. Certain mutations in this gene are known to cause distinct forms of muscular dystrophy. Alternative splicing results in multiple transcript variants, all encoding the same protein.

Molecular Weight

Observed_MW: 97kDa

Calculated_MW: 97kDa

Gene ID 1605
UniProt Q14118
Pathways Maintenance of Protein Location, Regulation of Carbohydrate Metabolic Process, Protein targeting to Nucleus
Application Notes WB 1:500 - 1:1000
Restrictions For Research Use only
Concentration 1 mg/mL
Buffer Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store at -20°C. Avoid freeze / thaw cycles.
Supplier Images
Image no. 1 for anti-Dystroglycan 1 (DAG1) antibody (ABIN6566766) Western blot analysis of extracts of various cell lines, using DAG1 antibody.