Synonyms: ATP dependent helicase SMARCA1,global transcription activator homologous sequence,ISWI,Nucleosome remodeling factor subunit SNF2L,NURF140,Probable global transcription activator SNF2L1,SMARCA1,SNF2-like 1,SNF2L,SNF2L1,SNF2LB,SNF2LT,sucrose nonfermenting 2-like protein 1,SWI,SWI/SNF related matrix associated actin dependent regulator of chromatin a1,SWI/SNF related matrix associated actin dependent regulator of chromatin subfamily a member 1,SWI2
Background: This gene encodes a member of the SWI/SNF family of proteins. The encoded protein is an ATPase which is expressed in diverse tissues and contributes to the chromatin remodeling complex that is involved in transcription. The protein may also play a role in DNA damage, growth inhibition and apoptosis of cancer cells. Alternative splicing results in multiple transcript variants.