Synonyms: CL P1,CL-P1,CLP1,COL12,COLEC 12,colec12,Collectin placenta 1,Collectin placenta protein 1,Collectin sub family member 12,Collectin-12,hCL P1,hCL-P1,NSR2,Nurse cell scavenger receptor 2,SCARA4,Scavenger receptor class A member 4,Scavenger receptor with C type lectin,Scavenger receptor with C-type lectin,SRCL
Background: This gene encodes a member of the C-lectin family, proteins that possess collagen-like sequences and carbohydrate recognition domains. This protein is a scavenger receptor, a cell surface glycoprotein that displays several functions associated with host defense. It can bind to carbohydrate antigens on microorganisms, facilitating their recognition and removal. It also mediates the recognition, internalization, and degradation of oxidatively modified low density lipoprotein by vascular endothelial cells.