MMP 9 antibody (Matrix Metallopeptidase 9 (Gelatinase B, 92kDa Gelatinase, 92kDa Type IV Collagenase))

Details for Product anti-MMP9 Antibody No. ABIN6567068
Antigen
Reactivity
Human, Mouse (Murine), Rat (Rattus)
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Host
Rabbit
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Clonality
Polyclonal
Conjugate
This MMP 9 antibody is un-conjugated
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Application
Immunohistochemistry (IHC), Western Blotting (WB)
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Options
Immunogen A synthetic peptide of human MMP9
Isotype IgG
Purification Affinity purification
Antigen
Alternative Name MMP9 (MMP9 Antibody Abstract)
Background

Synonyms: 82 kDa matrix metalloproteinase-9,92 kDa gelatinase,92 kDa type IV collagenase,CLG 4B,CLG4B,Collagenase Type 4 beta,Collagenase type IV 92 KD,EC 3.4.24.35,Gelatinase 92 KD,Gelatinase B,Gelatinase beta,GelatinaseB,GELB,Macrophage gelatinase,MANDP2,Matrix metallopeptidase 9 (gelatinase B,92  kDa gelatinase,92  kDa type IV collagenase),Matrix Metalloproteinase 9,MMP 9,MMP-9,MMP9,MMP9,Type V collagenase

Background: Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The enzyme encoded by this gene degrades type IV and V collagens. Studies in rhesus monkeys suggest that the enzyme is involved in IL-8-induced mobilization of hematopoietic progenitor cells from bone marrow, and murine studies suggest a role in tumor-associated tissue remodeling.

Molecular Weight

Observed_MW: 68kDa

Calculated_MW: 78kDa

Gene ID 4318
UniProt P14780
Pathways Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, CXCR4-mediated Signaling Events
Application Notes WB 1:200 - 1:500 IHC 1:100 - 1:200
Restrictions For Research Use only
Concentration 1 mg/mL
Buffer Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store at -20°C. Avoid freeze / thaw cycles.
Supplier Images
Image no. 1 for anti-Matrix Metallopeptidase 9 (Gelatinase B, 92kDa Gelatinase, 92kDa Type IV Collagenase) (MMP9) antibody (ABIN6567068) Immunohistochemistry of paraffin-embedded human esophagus using MMP9 antibody.
Image no. 2 for anti-Matrix Metallopeptidase 9 (Gelatinase B, 92kDa Gelatinase, 92kDa Type IV Collagenase) (MMP9) antibody (ABIN6567068) Western blot analysis of extracts of various cell lines, using MMP9 antibody.
Image no. 3 for anti-Matrix Metallopeptidase 9 (Gelatinase B, 92kDa Gelatinase, 92kDa Type IV Collagenase) (MMP9) antibody (ABIN6567068) Immunohistochemistry of paraffin-embedded mouse kidney using MMP9 antibody.
Image no. 4 for anti-Matrix Metallopeptidase 9 (Gelatinase B, 92kDa Gelatinase, 92kDa Type IV Collagenase) (MMP9) antibody (ABIN6567068) Immunohistochemistry of paraffin-embedded human liver injury using MMP9 antibody.