P21-Activated Kinase 6 (PAK6) antibody

Details for Product No. ABIN6571386
Antigen
  • PAK5
  • 4732456M09
  • pak6
  • si:ch211-158b22.3
  • p21 (RAC1) activated kinase 6
  • p21 protein (Cdc42/Rac)-activated kinase 6
  • p21 protein (Cdc42/Rac)-activated kinase 6b
  • PAK6
  • Pak6
  • pak6b
Reactivity
Human, Mouse (Murine), Rat (Rattus)
168
70
57
9
7
5
5
5
4
3
3
3
2
1
1
1
1
Host
Rabbit
171
1
Clonality
Polyclonal
Conjugate
Un-conjugated
7
6
5
5
5
5
3
3
3
3
3
3
2
2
2
2
2
Application
Immunohistochemistry (IHC), Western Blotting (WB)
120
59
51
30
26
20
17
5
5
2
1
1
Options
Immunogen Recombinant protein of human PAK6
Isotype IgG
Purification Affinity purification
Antigen
Alternative Name PAK6 (PAK6 Antibody Abstract)
Background

Synonyms: CDKN1A activated kinase 6,EC 2.7.1.37,p21 activated protein kinase 6,p21 protein (Cdc42/Rac)-activated kinase 6,p21(CDKN1A) activated kinase 6,p21-activated kinase 6,p21activated kinase 6,PAK 5,PAK 6,PAK-5,PAK-6,PAK5,Pak6,PAK6,Serine threonine protein kinase PAK 6,Serine/threonine protein kinase PAK 6,Serine/threonine protein kinase PAK6,Serine/threonine-protein kinase PAK 6

Background: This gene encodes a member of a family of p21-stimulated serine/threonine protein kinases, which contain an amino-terminal Cdc42/Rac interactive binding (CRIB) domain and a carboxyl-terminal kinase domain. These kinases function in a number of cellular processes, including cytoskeleton rearrangement, apoptosis, and the mitogen-activated protein (MAP) kinase signaling pathway. The protein encoded by this gene interacts with androgen receptor (AR) and translocates to the nucleus, where it is involved in transcriptional regulation. Changes in expression of this gene have been linked to prostate cancer. Alternative splicing results in multiple transcript variants.

Molecular Weight

Observed_MW: 75kDa

Calculated_MW: 69kDa/74kDa

Gene ID 56924
UniProt Q9NQU5
Application Notes WB 1:500 - 1:2000 IHC 1:50 - 1:200
Restrictions For Research Use only
Concentration 1 mg/mL
Buffer Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store at -20°C. Avoid freeze / thaw cycles.
Supplier Images
Image no. 1 for anti-P21-Activated Kinase 6 (PAK6) antibody (ABIN6571386) Western blot analysis of extracts of various cell lines, using PAK6 antibody.
Image no. 2 for anti-P21-Activated Kinase 6 (PAK6) antibody (ABIN6571386) Immunohistochemistry of paraffin-embedded human brain cancer using PAK6 antibody.
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