Synonyms: Rabbit Anti-Mouse IgG2b (Gamma 2b chain) Antibody DyLight 405™ Conjugated, Rabbit Anti Mouse IgG2b DyLight 405™ Conjugated Antibody
Background: Anti-Mouse IgG2b DyLight 405 Antibody generated in rabbit detects reactivity to Mouse IgG2b (Gamma 2b chain). Secreted as part of the adaptive immune response by plasma B cells, immunoglobulin G constitutes 75 % of serum immunoglobulins. IgG2, the second largest of IgG isotypes, comprises almost 25 % of IgG and has a low affinity for binding to the Fc receptor of phagocytic cells. Secondary Antibodies are available in a variety of formats and conjugate types. When choosing a secondary antibody product, consideration must be given to species and immunoglobulin specificity, conjugate type, fragment and chain specificity, level of cross-reactivity, and host-species source and fragment composition.