Hepatitis A Virus Cellular Receptor 2 (HAVCR2) antibody (APC)

Details for Product No. ABIN6728496
Antigen
  • HAVCR2
  • MGC140131
  • HAVcr-2
  • KIM-3
  • TIM3
  • TIMD-3
  • TIMD3
  • Tim-3
  • TIM-3
  • Tim3
  • Timd3
  • tim3
  • hepatitis A virus cellular receptor 2
  • HAVCR2
  • Havcr2
Reactivity
Mouse (Murine)
130
65
8
3
2
1
1
Host
Rat
103
46
24
8
Clonality (Clone)
Monoclonal ()
Conjugate
APC
13
12
12
9
6
3
2
2
2
2
2
2
2
Application
Flow Cytometry (FACS)
101
81
52
36
8
7
5
4
4
4
4
2
1
Options
Clone RMT3-23
Isotype IgG2a, kappa
Antigen
Alternative Name CD366/Tim-3 (HAVCR2 Antibody Abstract)
Background

Synonyms: TIM3, TIMD3,HAVcr-2,TIMD-3

Background: CD366 (Tim-3) is a transmembrane protein also known as T cell immunoglobulin and mucin domain containing protein-3. Tim-3 is expressed at high levels on activated T cells (preferentially on Th1 cells, monocytes/macrophages, and dendritic cells). Tim-3 has also been shown to exist as a soluble protein. Cells expressing Tim-3 are present at high levels in the CNS of animals at the onset of experimental autoimmune encephalomyelitis (EAE), a disease mediated by lymphocytes secreting Th1-like cytokines. Tim-3 has been proposed to inhibit Th1-mediated immune responses and promote immunological tolerance.

Gene ID 84868
UniProt Q8TDQ0
Pathways Regulation of Lipid Metabolism by PPARalpha
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Concentration 0.5 mg/mL
Buffer PBS with 0.05 % Proclin300, 1 % BSA
Preservative ProClin
Precaution of Use This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C
Storage Comment Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.
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