PEX5 antibody (AA 51-150) (Alexa Fluor 750)

Catalog No. ABIN6944512

Product Details anti-PEX5 Antibody (Alexa Fluor 750)

Target: PEX5 (Peroxisomal Biogenesis Factor 5 (PEX5))

Binding Specificity: AA 51-150

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PEX5 antibody is conjugated to Alexa Fluor 750

Application: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Cross-Reactivity: Mouse

Predicted Reactivity: Human,Rat,Dog,Cow,Sheep,Pig,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human PEX5

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for PEX5

Target: PEX5 (Peroxisomal Biogenesis Factor 5 (PEX5))

Alternative Name: PEX5 (PEX5 Products)

Synonyms: AW212715 antibody, ESTM1 antibody, PTS1R antibody, Pxr1 antibody, X83306 antibody, PTS1-BP antibody, PBD2A antibody, PBD2B antibody, PXR1 antibody, Peroxin-5 antibody, peroxisomal biogenesis factor 5 antibody, pex5 antibody, Pex5 antibody, PEX5 antibody

Background:

Synonyms: FLJ50634, FLJ50721, FLJ51948, Peroxin 5, Peroxin-5, Peroxisomal biogenesis factor 5, Peroxisomal C terminal targeting signal import receptor, Peroxisomal C-terminal targeting signal import receptor, Peroxisomal targeting signal 1 receptor, Peroxisome receptor 1, pex5, PEX5_HUMAN, PTS1 BP, PTS1 receptor, PTS1-BP, PTS1R, PXR1.

Background: The product of this gene binds to the C-terminal PTS1-type tripeptide peroxisomal targeting signal (SKL-type) and plays an essential role in peroxisomal protein import. Peroxins (PEXs) are proteins that are essential for the assembly of functional peroxisomes. The peroxisome biogenesis disorders (PBDs) are a group of genetically heterogeneous autosomal recessive, lethal diseases characterized by multiple defects in peroxisome function. The peroxisomal biogenesis disorders are a heterogeneous group with at least 14 complementation groups and with more than 1 phenotype being observed in cases falling into particular complementation groups. Although the clinical features of PBD patients vary, cells from all PBD patients exhibit a defect in the import of one or more classes of peroxisomal matrix proteins into the organelle. Defects in this gene are a cause of neonatal adrenoleukodystrophy (NALD), a cause of Zellweger syndrome (ZWS) as well as may be a cause of infantile Refsum disease (IRD). Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Oct 2008]

Gene ID: 5830

UniProt: P50542

Pathways: Monocarboxylic Acid Catabolic Process