PKC iota antibody (Protein Kinase C, iota) (AA 200-250) (HRP)

Details for Product anti-PRKCI Antibody No. ABIN6944557
Antigen
  • DXS1179E
  • PKCI
  • nPKC-iota
  • aPKC[l]
  • hal
  • has
  • PRKCI
  • PKC
  • 2310021H13Rik
  • AI427505
  • PKClambda
  • Pkci
  • Pkcl
  • Prkcl
  • aPKClambda
  • mKIAA4165
  • protein kinase C iota
  • protein kinase C, iota
  • PRKCI
  • prkci
  • Prkci
Epitope
AA 200-250
9
8
8
4
3
2
2
2
2
1
1
1
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
63
33
25
2
2
2
2
2
1
1
1
Host
Rabbit
55
8
Clonality
Polyclonal
Conjugate
This PKC iota antibody is conjugated to HRP
6
4
2
2
2
2
1
1
1
1
1
1
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
48
29
28
15
4
3
2
2
1
Options
Immunogen KLH conjugated synthetic peptide derived from human PKC iota/PKCI
Isotype IgG
Purification Purified by Protein A.
Plasmids, Primers & others Plasmids, Primers & others PKC iota products on genomics-online (e.g. as negative or positive controls)
Antigen
Alternative Name PKC iota (PRKCI Antibody Abstract)
Background

This gene encodes a member of the protein kinase C (PKC) family of serine/threonine protein kinases. The PKC family comprises at least eight members, which are differentially expressed and are involved in a wide variety of cellular processes. This protein kinase is calcium-independent and phospholipid-dependent. It is not activated by phorbolesters or diacylglycerol. This kinase can be recruited to vesicle tubular clusters (VTCs) by direct interaction with the small GTPase RAB2, where this kinase phosphorylates glyceraldehyde-3-phosphate dehydrogenase (GAPD/GAPDH) and plays a role in microtubule dynamics in the early secretory pathway. This kinase is found to be necessary for BCL-ABL-mediated resistance to drug-induced apoptosis and therefore protects leukemia cells against drug-induced apoptosis. There is a single exon pseudogene mapped on chromosome X. [provided by RefSeq, Jul 2008]


Synonyms: aPKC lambda/iota, aPKC-lambda/iota, Atypical protein kinase C lambda/iota, Atypical protein kinase C-lambda/iota, DXS1179E, KPCI_HUMAN, MGC26534, nPKC iota, nPKC-iota, nPKCiota, PKC lambda, PKCI, PKCiota, PKClambda, PRKC iota, PRKC lambda/iota, PRKC-lambda/iota, PRKCI, Protein kinase C iota, Protein kinase C iota type.
Gene ID 5584
UniProt P41743
Pathways Neurotrophin Signaling Pathway, Cell-Cell Junction Organization, Tube Formation
Application Notes IHC-P(1:200-400)
Restrictions For Research Use only
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % Gentamicin.
Preservative Gentamicin sulfate
Precaution of Use This product contains Gentamicin sulfate: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C
Expiry Date 12 months
Did you look for something else?