Plakophilin 4 antibody (AA 1101-1192) (HRP)

Catalog No. ABIN6944593

Product Details anti-Plakophilin 4 Antibody (HRP)

Target: Plakophilin 4 (PKP4)

Binding Specificity: AA 1101-1192

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Plakophilin 4 antibody is conjugated to HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Cross-Reactivity: Human

Predicted Reactivity: Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Plakophilin 4

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for Plakophilin 4

Target: Plakophilin 4 (PKP4)

Alternative Name: Plakophilin 4 (PKP4 Products)

Synonyms: p0071 antibody, 5031422I09Rik antibody, 9430019K17Rik antibody, Armrp antibody, PKP4 antibody, MGC146695 antibody, plakophilin 4 antibody, PKP4 antibody, Pkp4 antibody, pkp4 antibody

Background:

Synonyms: Catenin 4 , Catenin4 , FLJ31261 , FLJ42243 , p0071 , PKP 4 , PKP4 , PKP4_HUMAN , Plakophilin-4 , Plakophilin4.

Background: Armadillo-like proteins are characterized by a series of armadillo repeats, first defined in the Drosophila 'armadillo' gene product, that are typically 42 to 45 amino acids in length. These proteins can be divided into subfamilies based on their number of repeats, their overall sequence similarity, and the dispersion of the repeats throughout their sequences. Members of the p120(ctn)/plakophilin subfamily of Armadillo-like proteins, including CTNND1, CTNND2, PKP1, PKP2, PKP4, and ARVCF. PKP4 may be a component of desmosomal plaque and other adhesion plaques and is thought to be involved in regulating junctional plaque organization and cadherin function. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2015]

Gene ID: 8502

UniProt: Q99569

Pathways: Cell-Cell Junction Organization