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CD51/CD61 antibody

ITGAV/ITGB3 Reactivity: Human, Chicken FACS, IHC (fro), IP Host: Mouse Monoclonal 23C6 unconjugated
Catalog No. ABIN7013947
$350.66
Plus shipping costs $45.00
0.1 mg
Shipping to: United States
Delivery in 5 to 7 Business Days
  • Target See all CD51/CD61 (ITGAV/ITGB3) Antibodies
    CD51/CD61 (ITGAV/ITGB3) (ITGAV/ITGB3)
    Reactivity
    • 34
    • 20
    • 20
    • 6
    • 6
    • 5
    • 5
    • 5
    • 5
    • 2
    Human, Chicken
    Host
    • 20
    • 14
    Mouse
    Clonality
    • 20
    • 14
    Monoclonal
    Conjugate
    • 8
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CD51/CD61 antibody is un-conjugated
    Application
    • 29
    • 13
    • 13
    • 9
    • 7
    • 7
    • 6
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunoprecipitation (IP)
    Specificity
    The mouse monoclonal antibody 23C6 recognizes an extracellular epitope on CD51/CD61 complex, that is expressed mainly on human osteoclasts, but also e.g. on placenta, or melanoma cell lines. The epitope is native and sensitive to fixation. In chicken this antibody can be used to selectively identify the thrombocytes.
    No Cross-Reactivity
    Cow, Pig, Rabbit
    Purification
    Purified by protein-A affinity chromatography
    Immunogen
    A cell suspension containing osteoclasts from osteoclastomas
    Clone
    23C6
    Isotype
    IgG1
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Concentration
    1 mg/mL
    Buffer
    Phosphate buffered saline (PBS) solution with 15 mM sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C
    Storage Comment
    Store at 2-8°C. Do not freeze. Do not use after expiration date stamped on the label.
  • Target
    CD51/CD61 (ITGAV/ITGB3) (ITGAV/ITGB3)
    Alternative Name
    CD51/CD61 (ITGAV/ITGB3 Products)
    Synonyms
    CD51 antibody, MSK8 antibody, VNRA antibody, VTNR antibody, integrin subunit alpha V antibody, ITGAV antibody
    Background

    Description: CD51/CD61 (integrin alpha5beta3), also known as osteoclast functional antigen, serves as a vitronectin receptor, and binds also to fibronectin, fibrinogen, thrombospondin, osteopontin, collagen, and von Willebrand factor. Expression of this antigen increases with melanoma progression. In healthy individuals CD51/CD61 is expressed mainly on osteoclasts, placenta, and endothelial cells, at lower levels on platelets and macrophages.

    Other names: VNRA, MSK8, ITGB3, ITGAV, Integrin alpha5beta3, OFA, VR

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