MHC Class II HLA-DQ1/DQ3 antibody

Details for Product No. ABIN94338
Antigen
Reactivity
Human, Pig (Porcine)
7
3
Host
Mouse
7
Clonality (Clone)
Monoclonal ()
Application
Flow Cytometry (FACS), Immunoprecipitation (IP), Western Blotting (WB)
7
7
5
1
1
Options
Immunogen Burkitt's lymphoma cell line Raji.
Clone HL-37
Isotype IgG3
Specificity The antibody HL-37 reacts with polymorphic determinant on human HLA-DQ1 and HLA-DQ3 Molecules (recognized epitope was found on isolated beta chain of DQ1), but does not react with HLA-DQ2. DQ is the isotype of human MHC Class II molecules expressed on antigen-presenting cells (APC, dendritic cells, B lymphocytes, monocytes, macrophages).
Cross-Reactivity (Details) Human, Porcine
Purification Purified by protein-A affinity chromatography
Purity > 95 % (by SDS-PAGE)
Antigen
Alternative Name HLA-DQ1+DQ3
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Concentration 1 mg/mL
Buffer Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Do not freeze.
Storage 4 °C
Storage Comment Store at 2-8°C. Do not freeze. Do not use after expiration date stamped on vial label.
Supplier Images
Image no. 1 for anti-MHC Class II HLA-DQ1/DQ3 antibody (ABIN94338) Surface staining of human peripheral blood cells with anti-HLA-DQ1+DQ3 (HL-37) purifi...
Product cited in: Horejsí, N?mec, Angelisová, Kristofová, Gorga, Hilgert: "Characterization of seven new monoclonal antibodies against human DR, DR + DP and DQ1 + DQ3 antigens." in: Tissue antigens, Vol. 28, Issue 5, pp. 288-97, 1987 (PubMed).