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CHADL antibody (Chondroadherin-Like) Middle Region Primary Antibody

CHADL Reactivity: Human EIA, WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN951491
$682.00
Plus shipping costs $45.00
0.4 mL
Shipping to: United States
Available
  • Target See all CHADL products
    CHADL
    Binding Specificity
    • 8
    • 8
    • 7
    • 7
    • 1
    AA 405-434, Middle Region
    Reactivity
    • 24
    • 1
    • 1
    Human
    Host
    • 24
    Rabbit
    Clonality
    • 24
    Polyclonal
    Conjugate
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CHADL antibody is un-conjugated
    Application
    • 19
    • 16
    • 2
    • 1
    • 1
    Enzyme Immunoassay (EIA), Western Blotting (WB)
    Specificity
    This antibody reacts to CHADL.
    Cross-Reactivity (Details)
    Species reactivity (tested):Human.
    Purification
    Affinity chromatography on Protein A
    Immunogen
    KLH conjugated synthetic peptide between 405-434 amino acids from the Central region of human CHADL
    Isotype
    Ig Fraction
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.25 mg/mL
    Buffer
    PBS, 0.09 % (W/V) sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Target
    CHADL
    Alternative Name
    CHADL (CHADL Products)
    Synonyms
    SLRR4B, chondroadherin like, CHADL
    Background
    Members of the small leucine-rich proteoglycan (SLRP) family are mostly extracellular proteins that function upstream of multiple signaling cascades. They affect intracellular phosphorylation and modulate distinct pathways, such as those driven by Toll-like receptors, TGF? and receptor tyrosine kinases. As a member of the SLRP family, CHADL (Chondroadherin-like protein) is a 762 amino acid protein containing 21 LRR (leucine-rich) repeats, which promote protein-ligand interactions. Chondroadherin, a closely related protein, promotes attachment of chrondocytes, osteoblasts and fibroblasts and also plays an important role in the regulation of chrodrocyte proliferation and growth. CHADL is a secreted protein that is located in the extracellular space. There are two isoforms of CHADL that exist as a result of alternative splicing events.Synonyms: Chondroadherin-like protein, SLRR4B
    Molecular Weight
    Isoform2 74kd. 82388 Da
    Gene ID
    150356
    NCBI Accession
    NP_612490
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