This gene encodes a member of the IAP family of proteins that inhibit apoptosis by binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2, probably by interfering with activation of ICE-like proteases. The encoded protein inhibits apoptosis induced by serum deprivation but does not affect apoptosis resulting from exposure to menadione, a potent inducer of free radicals. It contains 3 baculovirus IAP repeats and a ring finger domain. Transcript variants encoding the same isoform have been identified.
Alternative names and synonyms associated with BIRC3
baculoviral IAP repeat-containing protein 3 (LOC100399118) ELISA Kit
inhibitor of apoptosis protein-2 (OpmnVgp074) ELISA Kit