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anti-Human BIRC5 Antibodies:
anti-Mouse (Murine) BIRC5 Antibodies:
anti-Rat (Rattus) BIRC5 Antibodies:
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Mouse (Murine) Polyclonal BIRC5 Primary Antibody for WB - ABIN3043511
Li, Zhao, Lu, Li, Yang, Wu, Liu: Notch-1 signaling promotes the malignant features of human breast cancer through NF-?B activation. in PLoS ONE 2014
Show all 6 Pubmed References
Human Polyclonal BIRC5 Primary Antibody for WB - ABIN3043195
Zhang, Lu, Hou, Hu, Wang: The effects of STAT3 and Survivin silencing on the growth of human bladder carcinoma cells. in Tumour biology 2014
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Human Polyclonal BIRC5 Primary Antibody for IHC (p), ELISA - ABIN3042792
Cai, Liu, Zhao, Wan, Hu, Zhou, Chen: Expressions of survivin and vascular endothelial growth factor in a Murine model of proliferative retinopathy. in International journal of ophthalmology 2012
Show all 4 Pubmed References
Human Monoclonal BIRC5 Primary Antibody for FACS - ABIN4895256
Mera, Magnusson, Tarkowski, Bokarewa: Extracellular survivin up-regulates adhesion molecules on the surface of leukocytes changing their reactivity pattern. in Journal of leukocyte biology 2007
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Human Monoclonal BIRC5 Primary Antibody for IF, IP - ABIN559893
Yamazaki, Fujiwara, Yukinaga, Ebisuya, Shiki, Kurihara, Kioka, Kambe, Nagao, Nishida, Masuda: The closely related RNA helicases, UAP56 and URH49, preferentially form distinct mRNA export machineries and coordinately regulate mitotic progression. in Molecular biology of the cell 2010
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Human Polyclonal BIRC5 Primary Antibody for CyTOF, FACS - ABIN4900855
Charalambous, Oks, Nchinda, Yamazaki, Steinman: Dendritic cell targeting of survivin protein in a xenogeneic form elicits strong CD4+ T cell immunity to mouse survivin. in Journal of immunology (Baltimore, Md. : 1950) 2006
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Human Monoclonal BIRC5 Primary Antibody for FACS - ABIN4895255
Perabo, Frössler, Landwehrs, Schmidt, von Rücker, Wirger, Müller: Indirubin-3'-monoxime, a CDK inhibitor induces growth inhibition and apoptosis-independent up-regulation of survivin in transitional cell cancer. in Anticancer research 2006
Human Monoclonal BIRC5 Primary Antibody for CyTOF, FACS - ABIN4898957
Schneider, Costa, Legrand, Bigot, Lecleire, Grassi, Vannier, Vasse: In vitro secretion of matrix metalloprotease 9 is a prognostic marker in childhood acute lymphoblastic leukemia. in Leukemia research 2010
Survivin expression in tumor tissue and its serum concetration significantly correlate with clinical and histopathological parameters in melanoma patients.
Data suggest that KLF4 (show KLF4 Antibodies) could promote cell senescence through a complex network: miR (show MLXIP Antibodies)-203, survivin, and p21 (show CDKN1A Antibodies), which were all regulated by overexpression of KLF4 (show KLF4 Antibodies) and contributed to cell senescence.
The high sensitivity, specificity, and accuracy of serum and aqueous humor survivin and TGF-B1 proteins make them promising markers for early detection and follow-up of RB patients.
increased expression of both DNA methytransferase I (DNMT1 (show DNMT1 Antibodies)) and Survivin was observed and significantly correlated with the reduced miR (show MLXIP Antibodies)-203 in NSCLC
ablation of Glut1 (show SLC2A1 Antibodies) attenuated apoptosis and increased drug resistance via upregulation of p-Akt (show AKT1 Antibodies)/p-GSK-3beta (show GSK3b Antibodies) (Ser9)/beta-catenin (show CTNNB1 Antibodies)/survivin.
Nuclear survivin expression correlates with endoglin (show ENG Antibodies)-assessed microvascularisation in laryngeal squamous cell carcinoma.
survivin expression modes and YAP (show YAP1 Antibodies) localization (Hippo pathway activation modes) were not correlated with survival. In addition, we confirmed that survivin small interference RNA (siRNA) transfection and YM155, an anti-survivin drug, elicited decreased nuclear survivin expression and cell proliferation in ISO-HAS-B cells which expressed survivin consistently
Survivin expression in lung squamous cell carcinoma was increased compared to normal tissue, and was unaffected by methylation status of the surviving gene.
Survivin gene promoter methylation was more frequent in gastric cancer patients than in controls.
These findings uncover the significance of Merlin (show NF2 Antibodies) protein expression and Survivin labeling index as prognosticators for poor clinical outcome in two independent Malignant pleural mesothelioma cohorts.
Survivin is important for optimal development of bovine blastocysts and confirm that survivin expression suppresses apoptosis of pre-implantation embryos.
Dermatoplasty can decrease spermatogenic cells and reduce Survivin protein expression.
Report survivin expression in the normal pancreas.
While induced by exposure to reactive oxygen species generating stresses, the ultimate expression of changes in radiation response is dependent upon the bi-functionality of the tumor associated protein survivin and its intracellular translocation.
HDL (show HSD11B1 Antibodies)-associated sphingosine 1-phosphate inhibits macrophage apoptosis by stimulating STAT3 (show STAT3 Antibodies) activity and survivin expression.
Survivin also attenuates DNA damage related to PARP (show PARP1 Antibodies) activation and inhibits TNFalpha (show TNF Antibodies)-induced lipolysis, suggesting that Survivin may facilitate adipocyte maintenance in response to inflammatory stimuli.
The study assigns a new meiotic function to Cullin9 and reveals that it prevents mouse eggs from aneuploidy by regulating microtubule dynamics via survivin.
this study shows that that sorafenib promotes the survival of bone marrow cells by up-regulating survivin
Survivin was regulated by TGF-beta (show TGFB1 Antibodies) and was found to be highly expressed during mucosal healing following intestinal inflammation
Survivin is a key regulator of gut (show GUSB Antibodies) tissue integrity by regulating epithelial homeostasis in the stem cell niche.
TGFbetaRI inhibition in an injured adult heart could both stimulate the autocrine/paracrine activity of survivin and inhibit Wnt (show WNT2 Antibodies) in CPCs to mediate cardioprotection and improve cardiac function.
Survivin is a key gene for regulating squamous cell carcinoma (SCC (show CYP11A1 Antibodies)) cancer stem cell formation and cancer SCC (show CYP11A1 Antibodies) development.
In colorectal cancer mice with downregulated expression of survivin, there were higher numbers of apoptotic cells and decreased expression levels of bcl2 (show BCL2 Antibodies) and ki67 (show MKI67 Antibodies).
This gene is a member of the inhibitor of apoptosis (IAP) gene family, which encode negative regulatory proteins that prevent apoptotic cell death. IAP family members usually contain multiple baculovirus IAP repeat (BIR) domains, but this gene encodes proteins with only a single BIR domain. The encoded proteins also lack a C-terminus RING finger domain. Gene expression is high during fetal development and in most tumors, yet low in adult tissues. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
baculoviral IAP repeat-containing 5 (survivin)
, baculoviral IAP repeat-containing protein 5
, baculoviral IAP repeat-containing 5 (survivin)-like
, apoptosis inhibitor survivin
, baculoviral IAP repeat-containing 5
, apoptosis inhibitor 4
, survivin variant 3 alpha