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anti-Rat (Rattus) BIRC5 Antibodies:
anti-Human BIRC5 Antibodies:
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Cat (Feline) Polyclonal BIRC5 Primary Antibody for ChIP, ELISA - ABIN153009
Blanc-Brude, Yu, Simosa, Conte, Sessa, Altieri: Inhibitor of apoptosis protein survivin regulates vascular injury. in Nature medicine 2002
Show all 298 Pubmed References
Human Monoclonal BIRC5 Primary Antibody for ELISA, FACS - ABIN153038
Zhu, Fukuda, Cordis, Das, Maulik: Anti-apoptotic protein survivin plays a significant role in tubular morphogenesis of human coronary arteriolar endothelial cells by hypoxic preconditioning. in FEBS letters 2001
Show all 31 Pubmed References
Human Monoclonal BIRC5 Primary Antibody for ELISA, FACS - ABIN153011
Ansell, Arendt, Grote, Jelinek, Novak, Wellik, Remstein, Bennett, Fielding: Inhibition of survivin expression suppresses the growth of aggressive non-Hodgkin's lymphoma. in Leukemia 2004
Show all 20 Pubmed References
Cat (Feline) Polyclonal BIRC5 Primary Antibody for ELISA, IHC (fro) - ABIN268915
Hauf, Cole, LaTerra, Zimmer, Schnapp, Walter, Heckel, van Meel, Rieder, Peters: The small molecule Hesperadin reveals a role for Aurora B in correcting kinetochore-microtubule attachment and in maintaining the spindle assembly checkpoint. in The Journal of cell biology 2003
Show all 18 Pubmed References
Human Monoclonal BIRC5 Primary Antibody for BP, ELISA - ABIN269272
Geddis, Kaushansky: Megakaryocytes express functional Aurora-B kinase in endomitosis. in Blood 2004
Show all 15 Pubmed References
Hamster Monoclonal BIRC5 Primary Antibody for ICC, IF - ABIN153037
Adida, Haioun, Gaulard, Lepage, Morel, Briere, Dombret, Reyes, Diebold, Gisselbrecht, Salles, Altieri, Molina: Prognostic significance of survivin expression in diffuse large B-cell lymphomas. in Blood 2000
Show all 14 Pubmed References
Cat (Feline) Polyclonal BIRC5 Primary Antibody for ELISA, ICC - ABIN268914
Kennedy, ODriscoll, Purcell, Fitz-Simons, McDermott, Hill, OHiggins, Parkinson, Linehan, Clynes: Prognostic importance of survivin in breast cancer. in British journal of cancer 2003
Show all 14 Pubmed References
Human Polyclonal BIRC5 Primary Antibody for WB - ABIN3043195
Li, Zhao, Lu, Li, Yang, Wu, Liu: Notch-1 signaling promotes the malignant features of human breast cancer through NF-?B activation. in PLoS ONE 2014
Show all 9 Pubmed References
Mouse (Murine) Polyclonal BIRC5 Primary Antibody for WB - ABIN3043511
Zhang, Lu, Hou, Hu, Wang: The effects of STAT3 and Survivin silencing on the growth of human bladder carcinoma cells. in Tumour biology 2014
Show all 9 Pubmed References
Human Polyclonal BIRC5 Primary Antibody for ICC, IF - ABIN153036
Liu, Brouha, Grossman: Rapid induction of mitochondrial events and caspase-independent apoptosis in Survivin-targeted melanoma cells. in Oncogene 2004
Show all 8 Pubmed References
Dermatoplasty can decrease spermatogenic cells and reduce Survivin protein expression.
Report survivin expression in the normal pancreas.
Survivin is important for optimal development of bovine blastocysts and confirm that survivin expression suppresses apoptosis of pre-implantation embryos.
Our findings identify survivin as a target of HO-1 (show HMOX1 Antibodies) and a mediator of adipocyte-induced survival in the metastatic niche.
High BIRC5 expression is associated with gefitinib resistance in lung cancer.
miR-203 expression also inhibited primary tumor growth in ovaries and metastatic tumors in multiple peritoneal organs including liver and spleen. miR-203 inhibits ovarian tumor metastasis by targeting BIRC5/survivin and attenuating the TGFbeta pathway.
Survivin may be implicated in the bcl-2 (show BCL2 Antibodies) and p53 (show TP53 Antibodies) pathways and therefore in the biology of PDAC. Its potential use as a survival predictor and therapeutic target represent a promising field.
Study in hepatocellular carcinoma cell line elicited a new mechanism in which IGF-1 induced epithelial-mesenchymal transition through regulation of survivin and a downstream pathway.
simvastatin significantly inhibited the proliferation and invasion of SACC83 cells, induced apoptosis, and reduced the expression of survivin, which suggests that simvastatin may be a novel target for salivary gland adenoid cystic carcinoma therapy.
Survivin is significantly up-regulated in hepatocellular carcinoma (HCC (show FAM126A Antibodies))tissues and associated with tumor growth and lymph node metastasis. Clinical detection of survivin level combined with MRI (show C7ORF49 Antibodies) examination might be beneficial for clinical diagnosis and treatment of HCC (show FAM126A Antibodies)
Our study identified the STAT3 (show STAT3 Antibodies) rs1053004 C/C as a high-risk genotype in MA with lower survivin and VEGF (show VEGFA Antibodies) transcription levels in the peripheral blood.
Overexpression of miR (show MLXIP Antibodies)-485-5p suppresses breast cancer progression and enhances chemosensitivity. Further study demonstrated that miR (show MLXIP Antibodies)-485-5p directly targeted the 3'-untranslated region of survivin and overexpression of survivin overcomes the miR (show MLXIP Antibodies)-485-5p induced effects on breast cancer.
Survivin expression in gastric cancer cells is regulated by DEC1 (show BHLHE40 Antibodies).
The present results indicated that PPARgamma (show PPARG Antibodies) may serve a protective role on bEnd.3 cells and that BIRC5 may be a downstream target of PPARgamma (show PPARG Antibodies) regulation during cerebral ischemia.
While induced by exposure to reactive oxygen species generating stresses, the ultimate expression of changes in radiation response is dependent upon the bi-functionality of the tumor associated protein survivin and its intracellular translocation.
HDL-associated sphingosine 1-phosphate inhibits macrophage apoptosis by stimulating STAT3 activity and survivin expression.
Survivin also attenuates DNA damage related to PARP activation and inhibits TNFalpha-induced lipolysis, suggesting that Survivin may facilitate adipocyte maintenance in response to inflammatory stimuli.
The study assigns a new meiotic function to Cullin9 and reveals that it prevents mouse eggs from aneuploidy by regulating microtubule dynamics via survivin.
this study shows that that sorafenib promotes the survival of bone marrow cells by up-regulating survivin
Survivin was regulated by TGF-beta (show TGFB1 Antibodies) and was found to be highly expressed during mucosal healing following intestinal inflammation
Survivin is a key regulator of gut (show GUSB Antibodies) tissue integrity by regulating epithelial homeostasis in the stem cell niche.
TGFbetaRI inhibition in an injured adult heart could both stimulate the autocrine/paracrine activity of survivin and inhibit Wnt (show WNT2 Antibodies) in CPCs to mediate cardioprotection and improve cardiac function.
Survivin is a key gene for regulating squamous cell carcinoma (SCC (show CYP11A1 Antibodies)) cancer stem cell formation and cancer SCC (show CYP11A1 Antibodies) development.
survivin2 is important in maintaining hematopoietic stem and lineage committed cells during zebrafish development, by virtue of its antiapoptotic activity in a caspase (show CASP3 Antibodies) dependent and cell autonomous fashion.
Survivin 2 was identified as a key regulator of neurogenesis, vasculo-angiogenesis, hematopoiesis and cardiogenesis.
This gene is a member of the inhibitor of apoptosis (IAP) gene family, which encode negative regulatory proteins that prevent apoptotic cell death. IAP family members usually contain multiple baculovirus IAP repeat (BIR) domains, but this gene encodes proteins with only a single BIR domain. The encoded proteins also lack a C-terminus RING finger domain. Gene expression is high during fetal development and in most tumors, yet low in adult tissues. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
apoptosis inhibitor survivin
, baculoviral IAP repeat-containing 5 (survivin)
, baculoviral IAP repeat-containing protein 5
, baculoviral IAP repeat-containing 5
, apoptosis inhibitor 4
, survivin variant 3 alpha
, baculoviral IAP repeat containing 5b
, baculoviral IAP repeat-containing 5B
, survivin 2
, baculoviral IAP repeat containing 5 S homeolog
, baculoviral IAP repeat-containing 5, gene 2