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Serum copeptin concentrations did not vary between the pregnancies complicated by intrahepatic cholestasis of pregnancy and the healthy pregnancy control group.
Copeptin appears to be an independent predictor of long-term mortality in a selected population of patients suspected for an acute coronary syndrome (ACS (show PLA2G15 Proteins)). In addition, copeptin may be considered as an early marker for the identification of patients at higher risk of the development of heart failure at long term in patients with acute chest pain.
High AVP expression is associated with gestational diabetes insipidus.
Data suggest that corticotrophin-releasing hormone (CRH (show CRH Proteins)) is able to stimulate copeptin release in healthy controls suggesting direct interaction of CRH/CRH (show CRH Proteins)-receptor signaling and vasopressin; these interactions appear to be altered in patients with pituitary disease; copeptin may be serum biomarker of altered CRH/CRH (show CRH Proteins)-receptor signaling in pituitary diseases.
copeptin might have a potential role in the pathogenesis of restless legs syndrome and be a biomarker for this disease.
Serum copeptin is a strong prognostic marker in both chronic obstructive pulmonary disease and acute heart failure.
Hypothalamic suprachiasmatic nucleus -AVP-ir showed a significant negative correlation with age in the control group and in the male, but not in the female depression group.
elevated plasma copeptin level is associated with an increased risk of heart failure (HF) and all-cause mortality in patients with HF.
Resistin (show RETN Proteins), but not copeptin levels are higher in acute ischemic stroke patients early after the stroke onset, than in age and gender matched stroke-free controls. Moreover, higher copeptin concentrations are predictive of poor short term functional outcome after ischemic stroke
Cord blood copeptin concentration does not seem to be a promising marker of acute kidney injury in asphyxiated neonates.
The abnormal social behaviors of Dio3 (show DIO3 Proteins)-/- mice were associated with sexually dimorphic alterations in the physiology of oxytocin (OXT) and arginine vasopressin (AVP), 2 neuropeptides with important roles in determining social interactions.
Data suggested that arginine vasopressin in the brain, not spinal cord and peripheral system of spinocerebellar ataxia type 3 mice related with the change of the spatial learning and memory of Morris water maze test.
The suprachiasmatic nucleus (SCN (show SRI Proteins))network consists of multiple clusters of cellular circadian rhythms that are differentially integrated by AVP and VIP (show Vip Proteins) signaling, depending on the postnatal period
These results identify G9a (show EHMT2 Proteins)-induced histone methylation at the OXT (show OXT Proteins) and AVP promoters in the Basolateral Amygdala as a mechanism for mediating stress-induced lasting behavioral depression and its reversal by exercise.
PDZ domain-containing protein Sipa1l1 (signal-induced proliferation-associated 1 like 1) binds to the cytoplasmic PDZ-ligand motif of aquaporin-2 and accelerates its endocytosis in the absence of vasopressin
Spatiotemporal profiles of arginine vasopressin (AVP) expression at the pixel level revealed circadian rhythms in the entire area of AVP-positive cells in the suprachiasmatic nucleus, and at least two clusters that showed different circadian oscillations.
Results suggest morphological and functional differences among the paraventricular nucleus' subnuclei and complex interactions among Chronic Unpredictable Stress, gonadal hormones and AVP immunoreactivity
Autophagy was induced in the AVP neurons subjected to endoplasmic reticulum stress in familial neurohypophysial diabetes insipidus mice.
A new role of PcG proteins in priming early-life stress-responsive DNA methylation (show HELLS Proteins) at the Avp enhancer prior to epigenetic programming.
The noradrenaline-nitric oxide pathway, which stimulates the expression of vasopressin, involves free radicals.
Atrial natriuretic peptide (show NPPA Proteins) and vasopressin-presence in the ciliary body of eye in the pig (sus domesticus).
This gene encodes a precursor protein consisting of arginine vasopressin and two associated proteins, neurophysin 2 and a glycopeptide, copeptin. Arginine vasopressin is a posterior pituitary hormone which is synthesized in the supraoptic nucleus and paraventricular nucleus of the hypothalamus. Along with its carrier protein, neurophysin 2, it is packaged into neurosecretory vesicles and transported axonally to the nerve endings in the neurohypophysis where it is either stored or secreted into the bloodstream. The precursor is thought to be activated while it is being transported along the axon to the posterior pituitary. Arginine vasopressin acts as a growth factor by enhancing pH regulation through acid-base transport systems. It has a direct antidiuretic action on the kidney, and also causes vasoconstriction of the peripheral vessels. This hormone can contract smooth muscle during parturition and lactation. It is also involved in cognition, tolerance, adaptation and complex sexual and maternal behaviour, as well as in the regulation of water excretion and cardiovascular functions. Mutations in this gene cause autosomal dominant neurohypophyseal diabetes insipidus (ADNDI).
, prepro-AVP-NP II
, prepro-arginine-vasopressin-neurophysin II
, vasopressin-neurophysin 2-copeptin
, vasopressin-neurophysin II-copeptin
, arginine vasopressin (Diabetes insipidus), same as Di (conflicting physical mapping)
, vasopressin-neurophysin prepropeptide
, arginine vasopressin-neurophysin II
, arginine vasopressin (neurophysin II, antidiuretic hormone, diabetes insipidus, neurohypophyseal)
, arginine vasopressin
, neurophysin 2
, arginine vasopressin (neurophysin 2, antidiuretic hormone, diabetes insipidus, neurohypophyseal)
, neurophysin II