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This gene encodes a member of the AP-2 family of transcription factors. AP-2 proteins form homo- or hetero-dimers with other AP-2 family members and bind specific DNA sequences. They are thought to stimulate cell proliferation and suppress terminal differentiation of specific cell types during embryonic development. Specific AP-2 family members differ in their expression patterns and binding affinity for different promoters. This protein functions as both a transcriptional activator and repressor. Mutations in this gene result in autosomal dominant Char syndrome, suggesting that this gene functions in the differentiation of neural crest cell derivatives.
transcription factor AP-2 beta (activating enhancer binding protein 2 beta)
, activating enhancer-binding protein 2 beta
, activating enhancer-binding protein 2-beta
, transcription factor AP-2-beta
, activating enhancer binding protein 2 beta
, transcription factor AP-2 beta
, AP2 transcription factor
, beta adaptin
, beta adaptin drosophila 1