Browse our GPS1 Proteins (GPS1)

Full name:: G Protein Pathway Suppressor 1 Proteins (GPS1)

On www.antibodies-online.com are 9 G Protein Pathway Suppressor 1 (GPS1) Proteins from 4 different suppliers available. Additionally we are shipping GPS1 Antibodies (107) and GPS1 Kits (7) and many more products for this protein. A total of 134 GPS1 products are currently listed.

Synonyms:: ARABIDOPSIS THALIANA FUSCA 6, ATFUS6, ATSK31, CONSTITUTIVE PHOTOMORPHOGENIC 11, COP9 SIGNALOSOME SUBUNIT 1, COP11, Cops1, csn1, EMB78, EMBRYO DEFECTIVE 78, FUSCA 6, im:6909260, im:7145572, R75577, Sgn1, SHAGGY-LIKE KINASE 31, SK31, zgc:154082

list all proteins	Gene Name	GeneID	UniProt
	GPS1	2873	Q13098
	GPS1	209318
	GPS1	117039	P97834
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GPS1 Proteins (GPS1) by Origin

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Relevant Pathways for GPS1 Proteins

Cell Division Cycle

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Human G Protein Pathway Suppressor 1 (GPS1) interaction partners

We identified recurrent mutations in the novel penile cancer tumor suppressor genes CSN1(GPS1) and FAT1
CSN1 (show CSN1S1 Proteins) appears to play a role not only in DNA repair but also in UV-induced apoptosis.
We analyzed whether CSN1 (show CSN1S1 Proteins) alone can increase DEN1 (show SENP8 Proteins) degradation in HeLa cells.these data suggest that the COP9 (show COPS8 Proteins) signalosome supports proteasome-dependent protein degradation of DEN1 (show SENP8 Proteins)/DenA in fungi and in human cells.
An increased level of CSN1 and CSN5 as an important part of the ubiquitin proteasome system (UPS) might be associated with the pathophysiology of preeclampsia.
CSN1 (show CSN1S1 Proteins) inhibits c-Jun (show JUN Proteins) phosphorylation without affecting its protein stability.
The N-terminal half of CSN1/GPS1 is required to repress c-fos expression and to inhibit AP-1 (show FOSB Proteins) and SRE transactivation, while the C-terminal half allows integration of the protein into the COP9 (show COPS8 Proteins) signalosome.

Mouse (Murine) G Protein Pathway Suppressor 1 (GPS1) interaction partners

The present study demonstrates that Asb-4 (show ASB4 Proteins) interacts with GPS1 and inhibits JNK (show MAPK8 Proteins) activity.

Arabidopsis thaliana G Protein Pathway Suppressor 1 (GPS1) interaction partners

TSA1 (show LY6E Proteins) interacts with CSN1 and is involved in Arabidopsis seedling development in darkness.
CSN1 can mediate COP1 nuclear translocation, and COP1 interacts with CSN1-NTD through its coiled-coil domain.

GPS1 Protein Profile

Protein Summary

This gene is known to suppress G-protein and mitogen-activated signal transduction in mammalian cells. The encoded protein shares significant similarity with Arabidopsis FUS6, which is a regulator of light-mediated signal transduction in plant cells. Two alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with GPS1

G protein pathway suppressor 1 (GPS1)
G protein pathway suppressor 1 (LOC693104)
G protein pathway suppressor 1 (CC1G_07518)
G protein pathway suppressor 1 (Bm1_55055)
G protein pathway suppressor 1 (Gps1)
G protein pathway suppressor 1 (gps1)
G protein pathway suppressor 1 L homeolog (gps1.L)
COP9 signalosome complex subunit 1 (FUS6)
COP9 signalosome complex subunit 1 (csn-1)

ARABIDOPSIS THALIANA FUSCA 6 protein
ATFUS6 protein
ATSK31 protein
CONSTITUTIVE PHOTOMORPHOGENIC 11 protein
COP9 SIGNALOSOME SUBUNIT 1 protein
COP11 protein
Cops1 protein
csn1 protein
EMB78 protein
EMBRYO DEFECTIVE 78 protein
FUSCA 6 protein
im:6909260 protein
im:7145572 protein
R75577 protein
Sgn1 protein
SHAGGY-LIKE KINASE 31 protein
SK31 protein
zgc:154082 protein

Protein level used designations for GPS1

COP9 signalosome complex subunit 1 , COP9 signalosome subunit 1 , GPS-1 , JAB1-containing signalosome subunit 1 , SGN1 , signalosome subunit 1 , G protein pathway suppressor 1 , MFH protein

GENE ID	SPECIES
2873	Homo sapiens
693104	Bombyx mori
6014597	Coprinopsis cinerea okayama7130
6105894	Brugia malayi
209318	Mus musculus
117039	Rattus norvegicus
777711	Danio rerio
431842	Xenopus laevis
417382	Gallus gallus
525572	Bos taurus
825286	Arabidopsis thaliana
180168	Caenorhabditis elegans
483377	Canis lupus familiaris
100713341	Cavia porcellus

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