Use your antibodies-online credentials, if available.
No Products on your Comparison List.
Your basket is empty.
Find out more
Show all synonyms
Select your origin of interest
Mouse (Murine) CCL2 Protein expressed in Escherichia coli (E. coli) - ABIN1305100
Ernst, Zhang, Hancock, Rutledge, Corless, Rollins: Biochemical and biologic characterization of murine monocyte chemoattractant protein-1. Identification of two functional domains. in Journal of immunology (Baltimore, Md. : 1950) 1994
Show all 5 Pubmed References
Rat (Rattus) CCL2 Protein expressed in Escherichia coli (E. coli) - ABIN1305099
Capsoni, Minonzio, Ongari, Zanussi: A new simplified single-filter assay for 'in vitro' evaluation of chemotaxis of 51Cr-labeled polymorphonuclear leukocytes. in Journal of immunological methods 1989
Show all 5 Pubmed References
Human CCL2 Protein expressed in Escherichia coli (E. coli) - ABIN935639
Frøyland, Pedersen, Kvissel, Almaas, Pharo, Skålhegg, Mollnes, Rootwelt: Effect of acidosis on IL-8 and MCP-1 during hypoxia and reoxygenation in human NT2-N neurons. in Brain research 2006
Show all 2 Pubmed References
Mouse (Murine) CCL2 Protein expressed in Escherichia coli (E. coli) - ABIN935595
Bogen, Dina, Gear, Levine: Dependence of monocyte chemoattractant protein 1 induced hyperalgesia on the isolectin B4-binding protein versican. in Neuroscience 2009
Show all 2 Pubmed References
Human CCL2 Protein expressed in Escherichia coli (E. coli) - ABIN1305101
Rollins, Stier, Ernst, Wong: The human homolog of the JE gene encodes a monocyte secretory protein. in Molecular and cellular biology 1990
Show all 2 Pubmed References
Mouse (Murine) CCL2 Protein expressed in Escherichia coli (E. coli) - ABIN413564
Zhu, Daghini, Chade, Rodriguez-Porcel, Napoli, Lerman, Lerman: Role of oxidative stress in remodeling of the myocardial microcirculation in hypertension. in Arteriosclerosis, thrombosis, and vascular biology 2006
Mouse (Murine) CCL2 Protein expressed in Escherichia coli (E. coli) - ABIN413594
Gray, Di Marco, Okabe, Szyndralewiez, Heitz, Montezano, de Haan, Koulis, El-Osta, Andrews, Chin-Dusting, Touyz, Wingler, Cooper, Schmidt, Jandeleit-Dahm: NADPH oxidase 1 plays a key role in diabetes mellitus-accelerated atherosclerosis. in Circulation 2013
CCL2 is associated with decreased recurrence-free survival in patients with basal-like breast cancer patients.
MCP-1 were up-regulated in macrophages cultured with cell-culture derived infectious HCV particles and promoted the migration of monocytes.
monocyte chemoattractant protein-1 (MCP-1), an endogenous CCR4 (show CCR4 Proteins)-binding ligand, was specifically upregulated in the head and neck squamous cell carcinomamicroenvironment compared to the other four CCR4 (show CCR4 Proteins)-binding ligands
Our findings indicate that the -2518 A/G MCP-1(CCL2) promoter gene polymorphism is associated with a higher risk of psoriasis.
Urine MCP-1 may detect early tubulointerstitial fibrosis in adults with normal kidney function.
p300 (show EP300 Proteins) inhibition attenuates both thrombin (show F2 Proteins) induced-CCL2 expression and histone H3 (show HIST3H3 Proteins) and H4 acetylation in HLFs, suggesting that p300 (show EP300 Proteins) is involved in thrombin (show F2 Proteins)-induced CCL2 expression via hyperacetylating histone H3 (show HIST3H3 Proteins) and H4.
in the presence of autologous platelets, monocytes from older adults synthesized greater MCP-1 than younger adults
Oral and periodontal innate immunity is affected by HIV viremia and ART. GCF (show GUCY2F Proteins) IL-8 (show IL8 Proteins), G-CSF (show CSF3 Proteins), as well as serum IL-8 (show IL8 Proteins), MCP-1 and GM-CSF (show CSF2 Proteins) may be useful biomarkers for the detection of disease presence and/or its severity due to HIV infection and ART use.
Peptide YY and PP are associated with circulating innate pro-inflammatory cytokines in patients after acute pancreatitis and cumulatively contribute to nearly half of the variance of IL-6 (show IL6 Proteins), MCP-1, and TNFalpha (show TNF Proteins). Future research is warranted to investigate the signaling pathways that underlie these associations.
The (show MLXIP Proteins) level of miR-33 was decreased, whereas the CCL2 level was increas (show MLXIP Proteins)ed in the articular cartilage from the osteoarthritis patients compared with the control group.
PDAC responds to radiotherapy by producing CCL2, which recruits Ly6C(+)CCR2(+) monocytes to support tumor proliferation and neovascularization after radiotherapy.
Chemokine receptor 2 (CCR2 (show CCR2 Proteins)(+)) monocytes invade the hippocampus between 1 and 3 d after SE. In contrast, only an occasional CD3 (show CD3E Proteins)(+) T lymphocyte was encountered 3 d after SE. The initial cellular sources of the chemokine (show CCL1 Proteins) CCL2, a ligand for CCR2 (show CCR2 Proteins), included perivascular macrophages and microglia. The induction of the proinflammatory cytokine IL-1beta (show IL1B Proteins) was greater in FACS-isolated microglia than in brain-invading monocytes
data suggest that MCP-1 (show CPT1B Proteins) may be a necessary component of the inflammatory response required for adipose tissue protection, remodeling and healthy expansion in the FVB/N strain in response to high-fat diet feedings
MCP-1 (show CPT1B Proteins) knockout mice exposed for voluntary wheel running displayed changes in brain cytokine expression and glial activation.
Carvedilol treatment also significantly reduced the levels of proinflammatory cytokines tumor necrosis factor (TNF)-alpha (show TNF Proteins), interleukin (IL)-1beta (show IL1B Proteins), IL-6 (show IL6 Proteins), transforming growth factor (TGF)-beta1 (show TGFB1 Proteins) and monocyte chemoattractant protein (MCP)-1 (show CPT1B Proteins) in the lung tissue.
Both IL-6 (show IL6 Proteins) protein production and transcript levels were downregulated by RA in respiratory tract epithelial cells (LETs) , but upregulated in macrophages (MACs). RA also increased transcript levels of MCP-1 (show CPT1B Proteins), GMCSF (show CSF2 Proteins), and IL-10 (show IL10 Proteins) in MACs, but not in LETs. Conversely, when LETs, but not MACs, were exposed to RA
FSAP (show HABP2 Proteins) deficiency causes an increase in CCL2 expression and CCL2-mediated infiltration of leukocytes into the injured vessel
miR (show MLXIP Proteins)-33 suppresses CCL2 expression via targeting at the 3'UTR. The miR (show MLXIP Proteins)-33/CCL2 axis in chondrocytes regulates the monocyte chemotaxis.
Sca-1(+) progenitor cells found to exhibit increased migration was associated with elevated levels of chemokines, CCL2 (chemokine (C-C motif) ligand 2) and CXCL1 (chemokine (C-X-C motif) ligand 1 (show CXCL1 Proteins)), and their corresponding receptors.
that MCP-1 (show CPT1B Proteins) inhibition restores glomerular endothelial glycocalyx and barrier function and reduces tissue inflammation in the presence of ongoing diabetic injury
resence of type 2 diabetes negatively affects the work of cytokines and markers of fibrosis, as evidenced by higher levels of interleukin-1beta and monocyte chemoattractant protein-1, compared with patients without diabetes
Studied SNPs in the bovine toll-like receptor 4 (TLR4 (show TLR4 Proteins)) and monocyte chemo attractant protein-1(CCL2) genes.
The LEP (show LEP Proteins), IGF2 and CCL2 genes showed allelic expression imbalance in liver, kidney and pituitary glands of Polish Holstein-Friesian bulls.
immune cells and endothelial cells can interact cooperatively to increase CCL2 secretion in the corpus luteum
ghrelin (show GHRL Proteins) can inhibit intraplaque angiogenesis and promote plaque stability by down-regulating VEGF (show VEGFA Proteins) and VEGFR2 (show KDR Proteins) expression, inhibiting the plaque content of macrophages, and reducing MCP-1 expression at an advanced stage of atherosclerosis in rabbits
Data show that peripheral blood endothelial progenitor cells can increase the expressions of chemokines CCL2 and CXCL12 (show CXCL12 Proteins) and promote the migration of enhanced green fluorescent protein-positive bone marrow stromal cells to bone defect site.
In a cerebral aneurysm, expression of MCP1 peaked after induction for one week, then decreased. MCP1 induced macrophage adhesion and infiltration in the artery wall of aneurysms, and contributed to the occurrence and development of brain aneurysm.
Data show that the serum levels of mast cell tryptase, monocyte chemoattractant protein-1 (MCP-1) and interleukin-8 (IL-8 (show IL8 Proteins)) decreased significantly in Dachengqi decoction treatment group.
measurements of CCL2 and macrophages can serve as new inflammatory biomarkers to evaluate the safety of promising novel microbicides for prevention of HIV.
Expression of MCP-1 was successfully inhibited by transfecting MCP-1 siRNA expression plasmid to the carotid artery, and the progression of atherosclerosis was restricted by RNAi-mediated silencing of MCP-1 expression.
CXCL10 (show CXCL10 Proteins) protein was detected in serum from pigs infected with a high virulence African swine fever virus isolate. Levels of CCL2 mRNA were increased in pigs infected with the high virulence isolate compared to a low virulence isolate.
Porcine CCL2 binding on Tuk4+SLA (show SLA Proteins)-II- but not on Tuk4-SLA (show SLA Proteins)-II+ cells was detected by using a CCL2-green fluorescence protein fusion protein.
The protective properties of flavonoids, such as EGCG, against endothelial inflammation may be regulated in part though induction of HO-1 and subsequent activator protein-1 signaling.
MCP-1 contributes to functional and structural impairment in the kidney in renal artery stenosis, mainly in the tubulointerstitial compartment
Contrast media did not affect bone marrow cell viability/MCP-1 secretion.
Porcine vessel wall injury via balloon arthroplasty upregulates expression of CCL2 by coronary artery transmural and perivascular cells in a sequential pattern.
in the aortic arch expression of monocyte chemoattractant protein 1 (MCP-1) was upregulated, compared with the thoracic aorta
Variable gene expression (eg, matrix metalloproteinase-9 (show MMP9 Proteins), CCL2 and Lp-PLA(2 (show Lp-PLA2 Proteins)) mRNAs), both in regard to the arterial bed and duration of disease, was associated with variable plaque development and progression.
myocardial infarction induced proinflammatory gene and protein expression in peripheral blood mononuclear cells of tissue factor (show F3 Proteins) cyclo-oxygenase-2, monocyte chemoattractant protein-1 and CRP (show CRP Proteins)
This gene is one of several cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The protein encoded by this gene is structurally related to the CXC subfamily of cytokines. Members of this subfamily are characterized by two cysteines separated by a single amino acid. This cytokine displays chemotactic activity for monocytes and basophils but not for neutrophils or eosinophils. It has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis and atherosclerosis. It binds to chemokine receptors CCR2 and CCR4.
small inducible cytokine A2
, C-C motif chemokine 2
, immediate-early serum-responsive JE protein
, immediate-early serum-responsive protein JE
, monocyte chemoattractant protein 1
, monocyte chemoattractant protein-1
, monocyte chemotactic protein 1
, small inducible gene JE
, small-inducible cytokine A2
, monocyte chemotactic and activating factor
, monocyte secretory protein JE
, small inducible cytokine A2 (monocyte chemotactic protein 1, homologous to mouse Sig-je)
, small inducible cytokine subfamily A (Cys-Cys), member 2
, platelet-derived growth factor-inducible protein JE
, acidic seminal fluid protein
, monocyte chemotactic protein 1A
, chemokine CCL2/MCP-1
, antiadrenocorticotropin peptide III
, corticostatin III
, macrophage antibiotic peptide MCP-1
, mast cell protease 1A