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Serum-expressed apolipoprotein B-100 (show APOB Proteins) protein, C9 Complement, and gelsolin (show GSN Proteins) can be used for differential diagnosis of Barrertts esophagus and adenocarcinoma of esophagus.
Patients with advanced atrophic AMD (show AMD1 Proteins) carried these rare variants more frequently than patients with neovascular AMD (show AMD1 Proteins) (11 of 93 [11.8%] vs 40 of 835 [4.8%]; P = .04).
Data indicate that complement C9 binds to the ATPase domain of mortalin (show HSPA9 Proteins).
Borrelial CspA binds the human terminal complement components C7 and C9 and blocks assembly and membrane insertion of the terminal complement complex (TCC (show SFXN1 Proteins)).
Caveolin-1 (show CAV1 Proteins) and dynamin-2 (show DNM2 Proteins) are essential for removal of the complement C5b-9 complex via endocytosis.
the haploinsufficiency of C9, a terminal complement complex component, engenders reduced intraocular secretion of VEGF (show VEGFA Proteins) and decreased risk for CNV development.
It was concluded that variations in the complement component 9 gene are unlikely to influence clearance of chronic hepatitis B virus infection and hepatocellular carcinoma occurrence.
Mapping the intermedilysin-human CD59 (show CD59 Proteins) receptor interface reveals a deep correspondence with the binding site on CD59 (show CD59 Proteins) for complement binding proteins C8alpha and C9.
These results suggested that the lack of membrane attack complex because of an Arg95Stop mutation of the complement component 9 gene predisposed patients to pathognomonic glomerulonephritis.
Complement C5b-9 induce a JNK (show MAPK8 Proteins)/Bid (show BID Proteins)-dependent and JNK (show MAPK8 Proteins)-independent necrotic cell death.
This gene encodes the final component of the complement system. It participates in the formation of the Membrane Attack Complex (MAC). The MAC assembles on bacterial membranes to form a pore, permitting disruption of bacterial membrane organization. Mutations in this gene cause component C9 deficiency.
complement component C9
, complement protein C9