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ERCC4 Antigen Profile
The protein encoded by this gene forms a complex with ERCC1 and is involved in the 5' incision made during nucleotide excision repair. This complex is a structure specific DNA repair endonuclease that interacts with EME1. Defects in this gene are a cause of xeroderma pigmentosum complementation group F (XP-F), or xeroderma pigmentosum VI (XP6).
Alternative names and synonyms associated with ERCC4
DNA excision repair protein ERCC-4
, DNA repair endonuclease XPF
, DNA repair protein complementing XP-F cells
, excision-repair, complementing defective, in Chinese hamster
, xeroderma pigmentosum group F-complementing protein
, xeroderma pigmentosum, complementation group F
, DNA repair endonuclease subunit
, Ercc4 protein-like
, excision repair cross-complementing rodent repair deficiency, complementation group 4
, DNA repair endonuclease XPF-like