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Human Polyclonal FBLN3 Primary Antibody for WB - ABIN515546
Márquez, Kohli, Arteta, Chang, Li, Goldblatt, Vidal-Vanaclocha: Identification of hepatic microvascular adhesion-related genes of human colon cancer cells using random homozygous gene perturbation. in International journal of cancer. Journal international du cancer 2013
Human Polyclonal FBLN3 Primary Antibody for FACS, IHC (p) - ABIN653039
Wakabayashi, Matsumine, Nakazora, Hasegawa, Iino, Ota, Sonoda, Sudo, Uchida: Fibulin-3 negatively regulates chondrocyte differentiation. in Biochemical and biophysical research communications 2010
Show all 2 Pubmed References
Cow (Bovine) Polyclonal FBLN3 Primary Antibody for WB - ABIN2776756
Weedon, Lango, Lindgren, Wallace, Evans, Mangino, Freathy, Perry, Stevens, Hall, Samani, Shields, Prokopenko, Farrall, Dominiczak, Johnson, Bergmann, Beckmann, Vollenweider, Waterworth, Mooser, Palmer, Morris, Ouwehand, Zhao, Li, Loos, Barroso, Deloukas, : Genome-wide association analysis identifies 20 loci that influence adult height. in Nature genetics 2008
Show all 2 Pubmed References
Data suggest that HIF2alpha (show EPAS1 Antibodies) mediates hypoxia-induced cancer growth/metastasis and that EFEMP1 is a downstream effector of hypoxia-induced HIF2alpha (show EPAS1 Antibodies) during breast tumorigenesis.
EFEMP1 suppresses epithelial-mesenchymal transition and migration in endometrial carcinoma
Results indicate that fibulin-3 serves as a pro-invasive factor in bladder cancer, which may be mediated through modulation of IGFBP5 (show IGFBP5 Antibodies) expression.
fibulin-3 confers a relatively high diagnostic efficacy and is acceptable to be an auxiliary biomarker to aid in malignant pleural mesothelioma identification.
FBLN-3 promoter region was highly methylated in some pancreatic cancer cell lines. FBLN-3 inhibited c-MET activation and expression and reduced cellular level of ALDH1 (show ALDH1A1 Antibodies).
Serum EFEMP1 is down-regulated and involved in the progression of Prostate Cancer. It may serve as a useful diagnostic biomarker, with better diagnostic accuracy than PSA in Prostate Cancer.
SMRP (show ABCC5 Antibodies) but not FBLN3 has a role in pleural effusions in in malignant pleural mesothelioma
EFEMP1 negatively modulates the migration ability in hepatocellular carcinoma. Reduction of EFEMP1 promotes the migration ability though increasing Matrix Metalloproteinase 2 (show MMP2 Antibodies) and Matrix Metalloproteinase 9 (show MMP9 Antibodies) expression via Extracellular Signal-Regulated MAP Kinase 1 (show MAPK3 Antibodies)/2 activity.
The EFEMP1 rs3791679 polymorphism influences glioma susceptibility in the Chinese Han population.
Extensive methylation of the EFEMP1 gene promoter can discriminate invasive from benign IPMNs with superior accuracy owing to their stepwise accumulation of tumor progression
TWEAK (show TNFSF12 Antibodies) promotes migration and invasion in murine embryonic fibroblasts through a mechanism dependent on ERKs activation and Fibulin 3 down-regulation.
Mutant fibulin-3 causes proteoglycan (show Vcan Antibodies) accumulation, reduction of MMP-2 (show MMP2 Antibodies) and MMP-9 (show MMP9 Antibodies), but increase of TIMP-3 (show TIMP3 Antibodies), and impairs diffusion across Bruch's membrane.
Define the Efemp1-p27(Kip1 (show CDKN1B Antibodies)) axis as a potential marker module of PDAC cell sensitivity towards dual PI3K-mTOR (show FRAP1 Antibodies) inhibitors.
The Efemp1 knock-in mice reconstitute the most important histopathologic symptoms of both Malattia leventinese and age-related macular degeneration.
fibulin-3 plays an important role in maintaining the integrity of fascia connective tissues and regulates aging.
both fibulin-3 and -5 are important in maintaining pelvic organ support in mice.
Data suggest a role for fibulin-3 in tissue maintenance and regeneration in the adult olfactory pathway.
This gene encodes a member of the fibulin family of extracellular matrix glycoproteins. Like all members of this family, the encoded protein contains tandemly repeated epidermal growth factor-like repeats followed by a C-terminus fibulin-type domain. This gene is upregulated in malignant gliomas and may play a role in the aggressive nature of these tumors. Mutations in this gene are associated with Doyne honeycomb retinal dystrophy. Alternatively spliced transcript variants that encode the same protein have been described.
EGF-containing fibulin-like extracellular matrix protein 1
, extracellular protein S1-5
, epidermal growth factor-containing fibulin-like extracellular matrix protein 1