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Human Monoclonal TGFb Primary Antibody for - ABIN577154
Nishiyama, McDonough, Bruns, Burgeson: Type XII and XIV collagens mediate interactions between banded collagen fibers in vitro and may modulate extracellular matrix deformability. in The Journal of biological chemistry 1994
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Human Polyclonal TGFb Primary Antibody for IHC (p), ELISA - ABIN2476753
Goldraich, Ramos, Goldraich: Urography versus DMSA scan in children with vesicoureteric reflux. in Pediatric nephrology (Berlin, Germany) 1990
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Cow (Bovine) Monoclonal TGFb Primary Antibody for ELISA, FACS - ABIN2476751
Mahan, Ballal, Nanda: Mitral valve tear complicating percutaneous valvuloplasty: diagnosis by transesophageal Doppler color flow mapping. in American heart journal 1991
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STAT3 (show STAT3 Antibodies) signaling is hyperactivated in systemic sclerosis in a TGFbeta (show TGFB1 Antibodies)-dependent manner
NOTCH1 (show NOTCH1 Antibodies) is a central mediator of TGFbetamediated FOXP3 (show FOXP3 Antibodies) expression and NOTCH1 (show NOTCH1 Antibodies) inhibition produces a significant reduction of melanoma cell proliferation and viability.
TET2 (show TET2 Antibodies) plays an important role in the pathogenesis of diabetic nephropathy by activating TGFbeta1 (show TGFB1 Antibodies) expression through demethylation of CpG islands in the TGFbeta1 (show TGFB1 Antibodies) regulatory region
Autocrine transforming growth factor-beta/activin (show Actbeta Antibodies) A (show INHBA Antibodies)-Smad (show SMAD1 Antibodies) signaling induces hepatic progenitor cells undergoing partial epithelial-mesenchymal transition states
epigallocatechin gallate and curcumin are potent in preventing Epithelial to mesenchymal transition induced by TGF-beta1 (show TGFB1 Antibodies) in ARPE-19 cells and therefore, proposed as potential molecules for further pre-clinical evaluation in Proliferative vitreoretinopathy management
TGFB1 (show TGFB1 Antibodies)-mediated PI3K (show PIK3CA Antibodies)/Akt (show AKT1 Antibodies) and p38 MAP kinase (show MAPK14 Antibodies) dependent alternative splicing of fibronectin (show FN1 Antibodies) extra domain A in human podocyte culture has been reported.
TGFB1 (show TGFB1 Antibodies) polymorphisms -509 C>T and +10 T>C are associated with Chagas disease susceptibility in a Brazilian population.
S100A4 (show S100A4 Antibodies) expression is induced by the TGF-beta (show TGFB1 Antibodies) pathway.
the results of the present study indicated that miR2145p may promote the adipogenic differentiation of BMSCs through regulation of the TGFbeta (show TGFB1 Antibodies)/Smad2 (show SMAD2 Antibodies)/COL4A1 (show COL4A1 Antibodies) signaling pathway, and potentially may be used to develop a novel drug for postmenopausal osteoporosis.
these results indicate that miR124 transection inhibits the growth and aggressive of osteosarcoma, potentially via suppression of TGFbetamediated AKT (show AKT1 Antibodies)/GSK3beta/snail (show SNAI1 Antibodies) family transcriptional repressor 1 (SNAIL1 (show SNAI1 Antibodies)) signaling, suggesting miR124 may be a potential anticancer agent/target for osteosarcoma therapy.
TGF-beta1 (show TGFB1 Antibodies) stimulated lubricin (show PRG4 Antibodies) secretion by superficial zone chondrocytes at all densities with twice-a-week TGF-beta (show TGFB1 Antibodies) treatment. It is noteworthy that the daily treatment of TGF-beta1 (show TGFB1 Antibodies) increased lubricin (show PRG4 Antibodies) much higher compared with twice-a-week treatment.
hypoxia increased the expression of platelet-derived growth factor (PDGF (show PDGFA Antibodies)) and transforming growth factor-beta1 (TGF-beta1 (show TGFB1 Antibodies)) and decreased the expression of neprilysin (NEP (show MME Antibodies)), which contributed to the hypoxia-induced Endothelial-to-mesenchymal transition of pulmonary artery endothelial cells.
TGF-beta1 (show TGFB1 Antibodies) modulates the expression of syndecan-4 (show SDC4 Antibodies) in cultured vascular endothelial cells in a biphasic manner.
Taken together, Staphylococcus aureus induces TGF-beta1 (show TGFB1 Antibodies) and bFGF (show FGF2 Antibodies) expression through the activation of AP-1 (show JUN Antibodies) and NF-kappaB (show NFKB1 Antibodies) in bovine mammary gland fibroblasts.
The results identify TGFB1 (show TGFB1 Antibodies) and ESRRA (show ESRRA Antibodies) as likely transcriptional regulators of rumen epithelial development and energy metabolism, respectively, and provide targets for modulation of rumen development and function in the growing calf.
the combined treatment with TGF-beta1 (show TGFB1 Antibodies) and BMP-7 (show BMP7 Antibodies) or treatment first with TGF-beta1 (show TGFB1 Antibodies) followed by BMP-7 (show BMP7 Antibodies) was more effective than other treatment groups in both chondrogenic differentiation and SZP (show PRG4 Antibodies) secretion.
Tenascin-X (show TNXB Antibodies) promotes activation of latent TGF-beta1 (show TGFB1 Antibodies) and subsequent epithelial to mesenchymal transition in mammary epithelial cells.
a detailed computational model for TGF-beta (show TGFB1 Antibodies) signalling that incorporates elements of previous models together with crosstalking between Smad1 (show SMAD1 Antibodies)/5/8 and Smad2 (show SMAD2 Antibodies)/3 channels through a negative feedback loop dependent on Smad7 (show SMAD7 Antibodies).
Endogenous TGF-beta1 (show TGFB1 Antibodies) became more bioactive following activation of the transgene protein product in chondrocytes.
A novel peptide, P2K, regulating TGF-beta1 (show TGFB1 Antibodies) signaling had an anabolic effect on bovine intervertebral disc cells and rabbit degenerated discs.
Data indicate that cardiac contractility modulation (CCM) therapy exerted protective effects against myocardial fibrosis potentially by inhibiting TGF-beta1 (show TGFB1 Antibodies)/Smad3 (show SMAD3 Antibodies) signaling pathway in chronic heart failure .
study suggested that TGF-beta1/Smad3/smad7 is a major pathway which plays an important role in the regulation of the IUA and specific inhibitor of Smad3 (SIS3) may provide a new therapeutic strategy for IUA.
cell therapy promoted TGF-beta1 (show TGFB1 Antibodies) expression in nucleus pulposus, leading to anti-inflammatory effects via the inhibition of NF-kappaB (show NFKB1 Antibodies), and the amelioration of disc degradation.
that prenatal tracheal occlusion increases TGF-beta (show TGFB1 Antibodies)/Rho kinase (show ROCK1 Antibodies) pathway, myofibroblast differentiation, and matrix deposition in neonatal rabbit and human congenital diaphragmatic hernia lungs
observation. Based on the above results, we conclude that TGF-beta1 (show TGFB1 Antibodies)-immobilized PLGA-gelatin scaffold seeded with ASCs considerably enhances the quality of the tissue-engineered cartilage, therefore, advancing the field of cartilage tissue engineering
Smad7 (show SMAD7 Antibodies) plays a crucial role in antagonizing epithelial-mesenchymal transition induced by TGFbeta (show TGFB1 Antibodies) signaling and is a Notch (show NOTCH1 Antibodies) signaling target in limbal epithelial stem cells.
the role of IL-10 in inhibited allograft rejection may be associated with CD4+CD25+ regulatory T cells and IL-10, and may be independent of TGF-b
After NOTCH1 (show NOTCH1 Antibodies) knockdown and TGFB1 (show TGFB1 Antibodies) stimulation, rabbit mesenchymal stem cells expressed higher levels of proteoglycan (show Vcan Antibodies) and collagen II.
TGF-beta1 (show TGFB1 Antibodies) gene transcription significantly correlates with the surgical vaginal and dermal wound closure rate.
TGF beta (show TGFB1 Antibodies) is involved in the pathogenesis of tympanosclerosis.
There was significantly higher expression of TGF-beta1 (show TGFB1 Antibodies) and MMP-9 (show MMP9 Antibodies) in nasal mucosa of experimental allergic rhinitis guinea pigs than in controls.
TGF-beta1 (show TGFB1 Antibodies) regulated pAKT (show AKT1 Antibodies) and IFNgamma expressions were associated with epithelial cell survival in rhesus macaque colon explants and suggest a potential role of mucosal TGF-beta1 (show TGFB1 Antibodies) in regulating intestinal homeostasis and EC integrity.
SIV infection of rhesus macaques results in the emergence of IL-17 (show IL17A Antibodies)-expressing cells during the acute phase. This subpopulation appears at day 14 postinfection concomitantly with an increase in TGF-beta (show TGFB1 Antibodies) and IL-18 (show IL18 Antibodies) expression.
SIV-infected macaques exhibiting progression to AIDS displayed greater expression of TGF-beta (show TGFB1 Antibodies) and indoleamine 2,3 dioxygenase in CD8 (show CD8A Antibodies)+ T cells from mesentric lymph nodes.
TGF-beta1 (show TGFB1 Antibodies) is activated or inactivated by MMP20 or KLK4 (show KLK4 Antibodies) and that the amelogenin (show AMELX Antibodies) cleavage product is necessary for the in-solution mobility of TGF-beta1 (show TGFB1 Antibodies).
Activated TGF-beta (show TGFB1 Antibodies) signaling rescued miR (show MYLIP Antibodies)-143-reduced FSHR (show FSHR Antibodies) and intracellular signaling molecules, and miR (show MYLIP Antibodies)-143-induced porcine granulosa cell apoptosis.
TGF-beta1 (show TGFB1 Antibodies)-induced epithelial-myofibroblast plasticity is FAK (show PTK2 Antibodies)- dependent, whereas TGF-beta1 (show TGFB1 Antibodies)-induced apoptosis is favored when FAK (show PTK2 Antibodies) signaling is inhibited.
this study shows that TGF-beta1 (show TGFB1 Antibodies) protects intestinal integrity and influences Smad (show SMAD1 Antibodies) and MAPK (show MAPK1 Antibodies) signal pathways in intestinal epithelium cells after TNF-alpha (show TNF Antibodies) challenge
this study shows that anemonin may ameliorate LPS (show IRF6 Antibodies)-induced intestinal injury and improve restoration by regulating the TGF-b1 and EGFR (show EGFR Antibodies) signaling pathways
The results indicated that TGF-beta-1 (show TGFB1 Antibodies) was associated with the restoration of intestinal morphology and barrier function following weaning stress.
Data (including data from in vitro and in vivo experiments) suggest that day 14 elongated conceptus secretes proteins that up-regulate TGFbeta1 (show TGFB1 Antibodies) mRNA and TGFbeta1 (show TGFB1 Antibodies) expression in endometrium; TGFbeta1 (show TGFB1 Antibodies) may be important during pregnancy maintenance.
The effects of semen, spermatozoa in extender, or extender alone on the expression of TGF-beta1 (show TGFB1 Antibodies), IL-10 (show IL10 Antibodies), and IL-6 (show IL6 Antibodies) in ovarian follicles are reported.
Dietary (1,3/1,6)-beta-D-glucan reduced the mRNA expression of transforming growth factor (TGF) beta2 (show TGFB2 Antibodies) and tended to reduce the mRNA expression of TGF-beta1 (show TGFB1 Antibodies) in lung tissue of neonatal piglet.
TGF-beta1 (show TGFB1 Antibodies), via TGF-beta1 (show TGFB1 Antibodies) receptor I and p38 MAPK (show MAPK14 Antibodies) signaling, reduces CFTR (show CFTR Antibodies) expression to impair CFTR (show CFTR Antibodies)-mediated anion secretion, which would likely compound the effects associated with mild CFTR (show CFTR Antibodies) mutations and ultimately would compromise male fertility.
RUNX1 (show RUNX1 Antibodies) promoted TGF-beta (show TGFB1 Antibodies)-induced partial EMT (show ITK Antibodies) by increasing transcription of the PI3K subunit p110delta, which mediated Akt (show AKT1 Antibodies) activation.
Transforming growth factor-beta1 induces cerebrovascular dysfunction and astrogliosis through angiotensin II type 1 receptor (show AGTR1 Antibodies)-mediated signaling pathways
early myocardial CTGF (show CTGF Antibodies) mRNA expression (six hours) after Ang-II (show AGT Antibodies) exposure is likely dependent on latent TGF-beta (show TGFB1 Antibodies) activation via the canonical Smad (show SMAD1 Antibodies)-dependent pathway in resident cardiac cells.
These results indicate that the hepatocytic expression of TGF-beta (show TGFB1 Antibodies) and CTGF (show CTGF Antibodies) is mediated by Wnt (show WNT2 Antibodies) signalling in Schistosoma japonicum infection.
Infection with Mycobacterium bovis results in increase in interleukin-1alpha, TGF-beta1 (show TGFB1 Antibodies), and MMP1 (show MMP1 Antibodies) in multinucleated macrophages.
type I and II IFN as in vivo modifiers of LIC fate that may significantly affect the impact of putative leukemia-driving activities such as the ETV6 (show ETV6 Antibodies)-RUNX1 (show RUNX1 Antibodies)-mediated growth advantage in the presence of TGF-beta (show TGFB1 Antibodies) and TLR4 (show TLR4 Antibodies)-upregulated mutagenic activity
Osthole,a natural coumarin, decreases the collagen/III ratio in transforming growth factor beta 1 (TGF-beta1 (show TGFB1 Antibodies))-transfected mouse cardiac fibroblasts via the TGF-beta (show TGFB1 Antibodies)/Smad (show SMAD1 Antibodies) signaling pathway.
both ERK (show EPHB2 Antibodies) and Smad2 (show SMAD2 Antibodies) signal pathways are involved in the activation of macrophages induced by TGF-b1 and high-ambient glucose, while there is no crosstalk shown in the process.
In obese mice, periodontitis caused the downregulation of MMP2 (show MMP2 Antibodies), and upregulation of TIMP1 (show TIMP1 Antibodies) and TGF-beta1 (show TGFB1 Antibodies) at transcriptional and translational levels
This gene encodes a member of the transforming growth factor beta (TGFB) family of cytokines, which are multifunctional peptides that regulate proliferation, differentiation, adhesion, migration, and other functions in many cell types. Many cells have TGFB receptors, and the protein positively and negatively regulates many other growth factors. The secreted protein is cleaved into a latency-associated peptide (LAP) and a mature TGFB1 peptide, and is found in either a latent form composed of a TGFB1 homodimer, a LAP homodimer, and a latent TGFB1-binding protein, or in an active form composed of a TGFB1 homodimer. The mature peptide may also form heterodimers with other TGFB family members. This gene is frequently upregulated in tumor cells, and mutations in this gene result in Camurati-Engelmann disease.
TGF-beta 1 protein
, latency-associated peptide
, transforming growth factor beta-1
, transforming growth factor, beta 1 (Camurati-Engelmann disease)
, transforming growth factor-beta 1
, transforming growth factor beta 1
, transforming growth factor-beta
, transforming growth factor beta1
, transforming growth factor-beta-1
, TGF-beta 1
, regulatory protein
, transforming growth factor, beta-1