Browse our Diencephalon/mesencephalon Homeobox 1 Proteins (DMBX1)

Full name:: Diencephalon/mesencephalon Homeobox 1 Proteins (DMBX1)

On www.antibodies-online.com are 6 Diencephalon/mesencephalon Homeobox 1 (DMBX1) Proteins from 3 different suppliers available. Additionally we are shipping Diencephalon/mesencephalon Homeobox 1 Antibodies (16) and Diencephalon/mesencephalon Homeobox 1 Kits (4) and many more products for this protein. A total of 34 Diencephalon/mesencephalon Homeobox 1 products are currently listed.

Synonyms:: Atx, Cdmx, dmbx1, mbx, mbx2, otx3, PAXB, pox1, zgc:112395, zMbx1

list all proteins	Gene Name	GeneID	UniProt
	DMBX1	127343	Q8NFW5
	DMBX1	140477	Q91ZK4
Rat DMBX1	DMBX1	313512
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Diencephalon/mesencephalon Homeobox 1 Proteins (DMBX1) by Origin

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Relevant Pathways for Diencephalon/mesencephalon Homeobox 1 Proteins

Feeding Behaviour

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More Proteins for Diencephalon/mesencephalon Homeobox 1 Interaction Partners

Human Diencephalon/mesencephalon Homeobox 1 (DMBX1) interaction partners

Results found that CpG sites of C1orf106, DMBX1, and SIK3 mediate the genetic risk of psoriasis in Chinese Han population.
no indications were found for an association between the MBX gene and microphthalmia with congenital cataract in humans

Mouse (Murine) Diencephalon/mesencephalon Homeobox 1 (DMBX1) interaction partners

The crystal structure of mouse ATX in complex with an anti-ATX aptamer.
Data (including data from studies in transgenic/knockout mice) suggest that expression in adult brain neurons (especially in parabrachial nucleus) of both Dmbx1 and AgRP (show AGRP Proteins) (agouti-related peptide) is important in appetite regulation leading to leanness.
Dmbx1, a novel evolutionarily conserved paired-like homeobox gene is expressed in the brain of mouse embryos. Linkage analysis mapped mouse Dmbx1 to the mid-portion of chromosome 4.
results suggest that Otx3 is a novel member of the Otx family and may be involved in the development of the central nervous system
Dmbx1 gene is expressed in the developing mouse diencephalon, midbrain and hindbrain, and has dynamic expression during forelimb and hindlimb development
Expression of Dmbx1 commences during gastrulation, when transcripts are detected in a crescent around the anterior neural plate. As development progresses, Dmbx1 marks the prospective midbrain and pretectum
Dmbx1 is expressed only in the developing central nervous system and in particular during early determination and successive differentiation of the midbrain and caudal diencephalon
Results demonstrate that Dmbx1 is required for postnatal survival, growth, and brain development.
Otx3/Dmbx1 represses Otx2-mediated transcription in the developing brain
Dmbx1 is essential for various actions of agouti-related protein (show AGRP Proteins) and plays a role in normal regulation of energy homeostasis and behavior

Zebrafish Diencephalon/mesencephalon Homeobox 1 (DMBX1) interaction partners

Mutual antagonism of the paired-type homeobox (show PRRX1 Proteins) genes, vsx2 (show VSX2 Proteins) and dmbx1, regulates retinal progenitor cell cycle exit upstream of ccnd1 (show CCND1 Proteins) expression.
Data suggest that both zebrafish dmbx1a and dmbx1b genes are retained in the fish genome due to their requirement during midbrain and retinal neurogenesis, although their function is partially diverged.
mbx homeobox (show PRRX1 Proteins) gene is required for the development of the eyes and tectum.
revealed a pattern of partial spatiotemporal expression divergence between the mbx paralogs that correlates with sequence divergence in noncoding regulatory domains

Diencephalon/mesencephalon Homeobox 1 (DMBX1) Protein Profile

Protein Summary

This gene encodes a member of the bicoid sub-family of homeodomain-containing transcription factors. The encoded protein acts as a transcription factor and may play a role in brain and sensory organ development. Two transcript variants encoding distinct isoforms have been identified for this gene.

Alternative names and synonyms associated with Diencephalon/mesencephalon Homeobox 1 (DMBX1)

diencephalon/mesencephalon homeobox 1 (DMBX1)
diencephalon/mesencephalon homeobox 1 (Dmbx1)
diencephalon/mesencephalon homeobox 1b (dmbx1b)
diencephalon/mesencephalon homeobox 1a (dmbx1a)

Atx protein
Cdmx protein
dmbx1 protein
mbx protein
mbx2 protein
otx3 protein
PAXB protein
pox1 protein
zgc:112395 protein
zMbx1 protein

Protein level used designations for DMBX1

diencephalon/mesencephalon homeobox protein 1 , homeoprotein MBX , orthodenticle homolog 3 , paired-like homeobox protein DMBX1 , paired-type homeobox Atx , diencephalon/mesencephalon homeobox 1 , diencephalon/mesencephalon-expressed brain homeobox 1 , diencephalon/mesencephalon-expressed brain homeobox gene 1 protein , homeobox gene Atx , orthodenticle 3 , diencephalon/mesencephalon homeobox protein 1-B , paired-type homeobox transcription factor Mbx2 , diencephalon/mesencephalon homeobox protein 1-A , diencephalon/mesencephalon-expressed brain homeobox gene 1 , etID309750.1 , homeoprotein Mbx , paired homeobox protein 1

GENE ID	SPECIES
127343	Homo sapiens
395271	Gallus gallus
469190	Pan troglodytes
540714	Bos taurus
610425	Canis lupus familiaris
100227965	Taeniopygia guttata
100342810	Oryctolagus cuniculus
100587686	Nomascus leucogenys
140477	Mus musculus
313512	Rattus norvegicus
550288	Danio rerio
142987	Danio rerio
100731695	Cavia porcellus

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