Browse our anti-FOSL2 (FOSL2) Antibodies

Human FOS-Like Antigen 2 (FOSL2) interaction partners

1. FOSL2 is a direct target of miR (show MLXIP Antibodies)-597 in breast cancer cells.

2. The binding and expression of c-Fos/Fra-2 increased as a function of severity of tongue lesions, yet selective participation of c-Jun appears to promote poor differentiation and aggressive tumorigenesis.

3. FOSL2 facilitates TGF-beta1 (show TGFB1 Antibodies)-induced migration by interaction with Smad3 (show SMAD3 Antibodies) in non-small cell lung cancer.FOSL2 positively regulates TGF-beta1 (show TGFB1 Antibodies) signalling .

4. FRA2 is a STAT5 (show STAT5A Antibodies) target gene regulated by IL-2 (show IL2 Antibodies) in human CD4 (show CD4 Antibodies) T cells.

5. we show that the suppression was mediated, at least in part, by a suspension culture-driven decrease in the levels of two members of the AP1 (show FOSB Antibodies) transcription factor complex, c-Jun (show JUN Antibodies) and Fra2

6. SOX4 is a direct target gene of FRA-2 and induces expression of HDAC8 (show HDAC8 Antibodies) in adult T-cell leukemia/lymphoma.

7. This study suggests that Fra-2 transgenic mice as an animal model of systemic sclerosis-associated pulmonary arterial hypertension display main characteristic features of the human disease.

8. results demonstrate the presence of a common oncogenic cascade initiated by FRA2/JUND (show JUND Antibodies) in CCR4 (show CCR4 Antibodies)-expressing mature T-cell malignancies such as ATLL and CTCLs

9. FOSL2 is a critical regulator of leptin (show LEP Antibodies) expression in adipocytes

10. Results suggest that Fra-2 protein may be more effective than ATF-2 (show ATF2 Antibodies) protein in cyst formation originated from epithelial cells of dental follicles.

Mouse (Murine) FOS-Like Antigen 2 (FOSL2) interaction partners

1. Fra-2 overexpression might impair myofibroblast functions crucial for secondary septation

2. Data show that Fos-Related Antigen-2 (Fra-2) is a key upstream regulator of forkhead box O1 (Foxo1 (show FOXO1 Antibodies)) and interferon regulatory factor 4 (Irf4 (show IRF4 Antibodies)) expression and influences proliferation and differentiation of B cells at multiple stages.

3. Deletion of Fra-2 leads to increased PPARgamma2 (show PPARG Antibodies) expression and adipocyte differentiation as well as increased adipocyte apoptosis through upregulation of hypoxia-inducible factors.

4. Osteoblast-specific expression of Fra-2/AP-1 (show JUN Antibodies) controls adiponectin and osteocalcin (show BGLAP Antibodies) expression and affects metabolism.

5. Cytokine-mediated Fra-2 expression and stabilization is linked to regulation of myogenic progenitor cells.

6. AP-1 (show JUN Antibodies) composed with JunD (show JUND Antibodies) and Fra2 protein plays a primary role in enhancing the transcription level of the CD11c (show ITGAX Antibodies) gene in dendritic cells

7. FOSL2 is a critical regulator of leptin (show LEP Antibodies) expression in adipocytes

8. Identify Fra-2 as an O(2)-sensitive transcriptional regulator of inducible TGFbeta (show TGFB1 Antibodies) expression and position Fra-2 as an important player in reoxygenation-induced myocardial fibrosis.

9. These findings reveal a novel function of Fra-2/AP-1 (show JUN Antibodies) as a positive regulator of bone and matrix formation in mice and humans.

10. Since transgenic overexpression of Fra-2 causes not only fibrosis but also vascular disease, Fra-2 might be an interesting novel candidate for molecular-targeted therapies for systemic sclerosis.

Zebrafish FOS-Like Antigen 2 (FOSL2) interaction partners

1. Fos-like antigen 2 (Fosl2), potentiates the rate of myocardial accretion from the zebrafish second heart field.